Wednesday, 20 June 2018 10:08

[EXPIRED] Postdoc in Microstructure Imaging of Hearing Loss

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We would like to invite applications for a 3-year postdoc position in microstructure imaging starting October 2018. The project has received funding from the Novo Nordisk Foundation under the interdisciplinary synergy program entitled UHeal “Uncovering Hidden Hearing Loss”. The aim of UHeal is to design imaging techniques and auditory methods to detect and diagnose a recently described noise induced hearing loss that a large part of the population has without really knowing it.

The postdoc project will focus on designing encoding waveforms for diffusion MRI and will use quantitative MRI acquisitions on a preclinical Bruker MRI scanner. Combined with biophysical models the acquisition should ensure contrast mechanisms for unravelling the underlying cell and axon density of noise induced changes in the inner ear and its nerve. The acquisition will be applied in animal models and validations will use histology and ultra-high 3D resolution synchrotron imaging. Finally, the acquisition must then be adapted to use on clinical scanners.

The postdoc will be part of the DRCMR Microstructure and Plasticity (MaP) group headed by Tim Dyrby, which is a dedicated cross-disciplinary and translational research team with the vision to improve the future non-invasive imaging technologies for better patient diagnosis. The project will be carried out at The Danish Research Centre for Magnetic Resonance (DRCMR) and is a synergistic collaboration with research teams at The Technical University of Denmark (DTU) and Harvard Medical School.

  • Application deadline: 15th August 2018
  • Starting date: is expected to be in October 2018

About us

The Danish Research Centre for Magnetic Resonance (DRCMR) is one of the leading research centers for biomedical MRI in Europe (www.drcmr.dk). Our mission is to triangulate MR physics and basic physiology from preclinical to clinical research. Approximately 75 researchers from a diverse range of disciplines are currently pursuing basic and clinically applied MR research and its validation with a focus on structural, functional, and metabolic MRI of the human brain and its disorders. The DRCMR is embedded in the Center for Functional and Diagnostic Imaging and Research, a large diagnostic imaging department including all biomedical imaging modalities at the Copenhagen University Hospital Hvidovre. DRCMR has a state-of-the-art MR-research infrastructure enabling translational research, which includes a pre-clinical 7T MR scanner, six whole-body MR scanners (one 7T, three 3T and two 1.5T scanners) and a High-Performance Computer cluster for neuroimaging. The DRCMR has pre-clinical labs, a neuropsychology laboratory, an EEG laboratory, and two laboratories for non-invasive brain stimulation.

The basic research microstructure and plasticity postdoc project will be centered around the newly installed 7T Bruker BioSpec MRI system, fully equipped with powerful gradients and a cryo-coil system. Varity of RF coils enables imaging of small tissue or phantom samples to whole brain ex vivo or in vivo rodents combined with optogenetic brain stimulation. The preclinical labs are fully equipped with e.g. electrophysiology facilities.

The ideal candidate

Should be an international oriented team player with:

  • A PhD degree or corresponding qualification in engineering, physics or computer science.
  • A strong documented background in experimental diffusion MRI and biophysical modeling.
  • Proficiency regarding MRI scanner software preferably for Bruker MRI and Paravision software.

Your tasks

  • To advance the field through your own research and its validation within microstructure imaging.
  • To work directly with a dedicated and inspiring team of preclinical researchers and collaborators.
  • Sequence development and optimization, biophysical modeling, simulations, data analysis and validation.
  • To be engaged in supervision of BSc, MSc and PhD students, knowledge dissemination and publishing in international, recognized scientific journals.

Your position

The candidate will be employed for a postdoc period of 36 months at the Danish Research Centre for Magnetic Resonance where he / she will be part of the Microstructure and Plasticity Group (drcmr.dk/map) and the Preclinical Method group, both led by Associate Professor Tim B. Dyrby.

Salary and Terms of Employment

Salary, pension and terms of employment are in accordance with the agreement between the Danish Regions (Danske Regioner) and the relevant professional organization. The salary depends on background education and seniority. Further supplements can be negotiated. Note that candidates coming from abroad may be eligible for tax reductions. The position is open for candidates of all nationalities.

We see diversity as a strength and encourage all persons regardless of gender, age, ethnicity, disabilities or religion to apply.

Applications should include a cover letter, CV and list of publications together with the names of three references. Applications must be submitted on-line through the RegionH job portalclick here.

Applications are reviewed on a rolling basis with the deadline to apply August 15th, 2018. The position will be filled as soon as a well-qualified person is identified.

For further information regarding the position please contact Associate Professor Tim B. Dyrby  

Direct line: +45 3862 6542; Email: