Mathiesen HK;Nielsen AS;Nielsen K;Hanson LG
[Magnetic resonance spectroscopy in the evaluation of cognitive disturbances.]
Ugeskr Laeger 2006, 168(4), , 357-359
Magnetic resonance spectroscopy can detect metabolic changes in the brain, including changes in N-acetyl aspartate, a metabolite generally believed to be a marker of neuronal integrity. The correlations between metabolic changes and cognitive status in normal subjects and in a range of neurological and psychiatric disorders are reviewed. Magnetic resonance spectroscopy seems to be a way to monitor the efficacy of existing and new treatments to prevent the development of cognitive deficits in a number of diseases