Björn Sigurðsson

Tuomas O Lilius, Kristian Nygaard Mortensen, Claire Deville, Terhi J Lohela, Frederik Filip Stæger, Björn Sigurdsson, Elisabetta M Fiordaliso, Marko Rosenholm, Chris Kamphuis, Freek J Beekman, Andreas I Jensen, Maiken Nedergaard. Glymphatic-assisted perivascular brain delivery of intrathecal small gold nanoparticles. https://doi.org/10.1016/j.jconrel.2023.01.054, 2023. Journal of Controlled Release.

Björn Sigurdsson*, Natalie L Hauglund*, Tuomas O Lilius, Frida LH Mogensen, Kristian N Mortensen, Natalie Beschorner, Laura Klinger, Simone L Bærentzen, Marko P Rosenholm, Vladimir Shalgunov, Matthias Herth, Yuki Mori, Maiken Nedergaard. A SPECT-based method for dynamic imaging of the glymphatic system in rats. https://doi.org/10.1177/0271678X231156982. 2023. Journal of Cerebral Blood Flow & Metabolism.

Tuomas O Lilius, Marko Rosenholm, Laura Klinger, Kristian Nygaard Mortensen, Björn Sigurdsson, Frida Lind-Holm Mogensen, Natalie L Hauglund, Malthe Skytte Nordentoft Nielsen, Tomi Rantamäki, Maiken Nedergaard. SPECT/CT imaging reveals CNS-wide modulation of glymphatic cerebrospinal fluid flow by systemic hypertonic saline. https://doi.org/10.1016/j.isci.2022.105250. 2022. Iscience.

Celia Kjaerby, Mie Andersen, Natalie Hauglund, Verena Untiet, Camilla Dall, Björn Sigurdsson, Fengfei Ding, Jiesi Feng, Yulong Li, Pia Weikop, Hajime Hirase, Maiken Nedergaard. Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine. https://doi.org/10.1038/s41593-022-01102-9. 2022. Nature neuroscience.

Evan Hunter Stanton, Niklas Daniel Åke Persson, Ryszard Stefan Gomolka, Tuomas Lilius, Björn Sigurðsson, Hedok Lee, Anna Lenice Ribeiro Xavier, Helene Benveniste, Maiken Nedergaard, Yuki Mori. Mapping of CSF transport using high spatiotemporal resolution dynamic contrast‐enhanced MRI in mice: effect of anesthesia. https://doi.org/10.1002/mrm.28645. 2021. Magnetic Resonance in Medicine.

Frederik Filip Stæger, Kristian Nygaard Mortensen, Malthe Skytte Nordentoft Nielsen, Björn Sigurdsson, Louis Krog Kaufmann, Hajime Hirase, Maiken Nedergaard. A three-dimensional, population-based average of the C57BL/6 mouse brain from DAPI-stained coronal slices. https://doi.org/10.1038/s41597-020-0570-z. 2020. Scientific Data.

Xiaowei Wang, Nanhong Lou, Allison Eberhardt, Yujia Yang, Peter Kusk, Qiwu Xu, Benjamin Förstera, Sisi Peng, Meng Shi, Antonio Ladrón-de-Guevara, Christine Delle, Björn Sigurdsson, Anna LR Xavier, Ali Ertürk, Richard T Libby, Lu Chen, Alexander S Thrane, Maiken Nedergaard. An ocular glymphatic clearance system removes β-amyloid from the rodent eye. https://doi.org/10.1126/scitranslmed.aaw3210. 2020. Science translational medicine.

Anne Sofie Munk, Wei Wang, Nicholas Burdon Bechet, Ahmed M Eltanahy, Anne Xiaoan Cheng, Björn Sigurdsson, Abdellatif Benraiss, Maarja A Mäe, Benjamin Travis Kress, Douglas H Kelley, Christer Betsholtz, Kjeld Møllgård, Anja Meissner, Maiken Nedergaard, Iben Lundgaard. PDGF-B is required for development of the glymphatic system. https://doi.org/10.1016/j.celrep.2019.02.050. 2019. Cell reports.

Lauren M Hablitz, Hanna S Vinitsky, Qian Sun, Frederik Filip Stæger, Björn Sigurdsson, Kristian N Mortensen, Tuomas O Lilius, Maiken Nedergaard. Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia. https://doi.org/10.1126/sciadv.aav5447. 2019. Science advances.

Björn Sigurdsson, Sune Darkner, Stefan Horst Sommer, Kristian Nygaard Mortensen, Simon Sanggaard, Serhii Kostrikov, Maiken Nedergaard. Brain Segmentation in Rodent MR-Images Using Convolutional Neural Networks. 2018. Joint Annual Meeting ISMRM-ESMRMB 2018.