Kristian Nygaard Mortensen
Tel.
+45 3862 0505
Position
Postdoc
Research Interests
Cerebral blood flow and metabolism, cerebrospinal fluid flows, kinetic modelling
Research Groups
Ultra-High Field MR group
Curriculum Vitae
Education
2022
PhD in Neuroscience, University of Copenhagen
2014
MSc in Computer Science, University of Copenhagen
2011
BSc in Computer Science, University of Copenhagen
Employments
2022 - Present
Postdoc at DRCMR
2019 - 2022
PhD student at Center for Translational Neuromedicine, University of Copenhagen
2016 - 2018
Research assistant at Center for Translational Neuromedicine, University of Copenhagen
2015 - 2015
Research Assistant at the Magnetic Resonance Research Center, Yale school of medicine
Publications
T. Du, H. Mestre, B. T. Kress, G. Liu, A. M. Sweeney, A. J. Samson, M. K. Rasmussen, K. N. Mortensen, P. A. R. Bork, W. Peng, G. E. Olveda, L. Bashford, E. R. Toro, J. Tithof, D. H. Kelley, J. H. Thomas, P. G. Hjorth, E. A. Martens, R. I. Mehta, H. Hirase, Y. Mori, M. Nedergaard, Cerebrospinal fluid is a significant fluid source for anoxic cerebral oedema. Brain (2021), doi:10.1093/brain/awab293.
F. F. Stæger*, K. N. Mortensen*, M. S. N. Nielsen, B. Sigurdsson, L. K. Kaufmann, H. Hirase, M. Nedergaard, A three-dimensional, population-based average of the C57BL/6 mouse brain from DAPI-stained coronal slices. Sci Data. 7, 235 (2020).
H. Mestre, T. Du, A. M. Sweeney, G. Liu, A. J. Samson, W. Peng, K. N. Mortensen, F. F. Stæger, P. A. R. Bork, L. Bashford, E. R. Toro, J. Tithof, D. H. Kelley, J. H. Thomas, P. G. Hjorth, E. A. Martens, R. I. Mehta, O. Solis, P. Blinder, D. Kleinfeld, H. Hirase, Y. Mori, M. Nedergaard, Cerebrospinal fluid influx drives acute ischemic tissue swelling. Science. 367, eaax7171 (2020).
K. N. Mortensen, S. Sanggaard, H. Mestre, H. Lee, S. Kostrikov, A. L. R. Xavier, A. Gjedde, H. Benveniste, M. Nedergaard, Impaired Glymphatic Transport in Spontaneously Hypertensive Rats. J Neurosci. 39, 6365–6377 (2019).
S. Koundal, X. Liu, S. Sanggaard, K. N. Mortensen, J. Wardlaw, M. Nedergaard, H. Benveniste, H. Lee, Brain Morphometry and Longitudinal Relaxation Time of Spontaneously Hypertensive Rats (SHRs) in Early and Intermediate Stages of Hypertension Investigated by 3D VFA-SPGR MRI. Neuroscience. 404, 14–26 (2019).
L. M. Hablitz, H. S. Vinitsky, Q. Sun, F. F. Stæger, B. Sigurdsson, K. N. Mortensen, T. O. Lilius, M. Nedergaard, Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia. Sci Adv. 5, eaav5447 (2019).
K. N. Mortensen, A. Gjedde, G. J. Thompson, P. Herman, M. J. Parent, D. L. Rothman, R. Kupers, M. Ptito, J. Stender, S. Laureys, V. Riedl, M. T. Alkire, F. Hyder, Impact of Global Mean Normalization on Regional Glucose Metabolism in the Human Brain. Neural Plast. 2018, 6120925 (2018).
H. Lee, K. N. Mortensen, S. Sanggaard, P. Koch, H. Brunner, B. Quistorff, M. Nedergaard, H. Benveniste, Quantitative Gd‐DOTA uptake from cerebrospinal fluid into rat brain using 3D VFA‐SPGR at 9.4T. Magnet Reson Med. 79, 1568–1578 (2018).
J. Stender*, K. N. Mortensen*, A. Thibaut, S. Darkner, S. Laureys, A. Gjedde, R. Kupers, The Minimal Energetic Requirement of Sustained Awareness after Brain Injury. Curr Biol. 26, 1494–1499 (2016).