Course title: Magnetic Resonance Imaging Basics

Content and format: The course provides a basis for understanding MRI measurements, pitfalls and literature. The course is not practically enabling, but provides a starting point for further studies. It covers introductory MRI acquisition in a series of ~7 weekly interactive lectures starting October 1st, 2024. These include MR basics, acquisition methods and parameters with a focus on understanding. Detailed topics are described below. Active participation is required. 

The course starts at a level requiring little or no MR experience, and a technical background is not required. The target audience is employees and students at the MR department but the course is open for external participants (a fee may apply -- see below). 

The course also gives a good basis for attending the independent and more technical spring course Medical Magnetic Resonance Imaging offered as part of the Biomedical Engineering program at the Technical University of Denmark, which is also available for non-DTU-students (offered under "Open University". Note that math & programming skills are required for the DTU course).

Dates, time, place: The course starts Tuesday afternoon 13:00-16:00, October 1st, 2024. With possible exceptions, the course continues weekly until around November 12th (tentative lecture plan below). It will mostly be in room 2 in the HH's educational  building outside the hospital's main entrance (November 5th, room 7 there is used instead). This page will be updated below to specify details. Let me know if there are time conflicts affecting several several participants on a particular Tuesday (e.g., autumn holliday? If so, the lecturing may be cancelled).

Registration: The  course is open, but subject to a fee of DKK 5000 unless you are sufficiently connected to the DRCMR. Ask Karam Sidaros if in doubt (), and sign up to Lars () including info about your affiliation, and payment details, if relevant ("EAN number", address and reference). You will then be added to the course mailing list.

Literature and software: The course is initially based on notes http://eprints.drcmr.dk/37/ (also available in Danish). Other course notes, slides and relevant articles are provided during the course.

Credit: The course has a workload corresponding to 1.5 ECTS points. You do not, however, automatically get credit for the course in any education. You can get a certificate and apply for credit at your school, but be aware that no general evaluation is planned, which may be required for a credit-bearing course. An informal exam focused on your particular interests can be arranged on an individual basis upon request. This is required for the organizer to recommend 2 ECTS in total (up to 2.5 depending on assignments/exams. The DRCMR safety courses can also count).

Language: The course language is English. Participants are welcome to respond and ask questions in Danish, if preferred.

Organizer and lecturer:  Lars G. Hanson (senior scientist at DRCMR, and associate professor at the MR section, DTU).

Preliminary outline divided on weeks (more precise updates are sent to participants):

October 1st, Part 1 (room 2 in the HH's educational  building):

• Sections "Magnetic Resonance" until "Sequences" in MR notes are discussed during the coming few weeks (the English and Danish versions are similar). Protons, spin, net magnetization, precession, radio waves, resonance, relaxation, rotating and stationary frames of reference, T1 and T2.

October 8th, Part 2 (same location as above):

• Relaxation time weighting. Sequence diagrams, contrast, inversion, saturation

October 15th, Part 3 (same location as above) if not cancelled due to autumn school holiday (inform Lars if cancellation is preferred):

• Dephasing, refocusing, T2*, spin echoes
• Frames of reference
• Magnetic interaction with tissue
• Shimming
• Low tip angle excitation (FLASH)
• Excitation dynamics in rotating frame of reference
• Sources of contrast
• Sequence building blocks: Inversion, saturation, lipid/water suppression.

MR notes from "Imaging" and beyond are covered during the coming weeks.

Part 4:

• Gradients, slice selection
• Phase, phase rolls
• Imaging and k-space. Echo time revisited.

Part 5:

• k-space trajectories, artifacts (distortions, ghosting and aliasing), noise and image quality quantification.
• Sequence and weighting follow-up, BOLD contrast.

Part 6:

• Diffusion weighting and fMRI.

Part 7:

• Left-overs and other content to be decided, e.g. spectroscopy.

The lecture plan may be adjusted with respect to both location, subjects and timing, to some degree based on participant wishes. Updates are distributed to registered participants (see above).