A PhD course on Statistical parametric mapping of functional and structural magnetic resonance imaging (MRI) data of the human brain is offered at Hvidovre Hospital in Copenhagen, September 2010. The course is organized in collaboration with the Functional Imaging Unit at Glostrup Hospital, and DTU Informatics at the Technical University of Denmark.
Registration: http://phdkursus.sund.ku.dk/frontPlanner/DetailKursus.aspx?id=95500
This PhD course will provide a theoretical and practical introduction to the pre-processing and statistical analysis of magnetic resonance imaging (MRI) data sets of the human brain. Participants will learn to use one of the most widely used neuroimaging analysis software packages (SPM - Statistical Parametric Mapping, http://www.fil.ion.ucl.ac.uk/spm/) which provides powerful means to analyse functional and structural MRI data.
Specific aims:
The course participants’ should at the end of the course have learnt
- the basic pre-processing steps of MRI data analysis,
- to set-up an appropriate first-level (subject level) statistical model that optimally captures the experimental design and potentially confounding variables (e.g., head movements),
- to perform statistical analyses at the second level (group level) and between groups,
- to include performance measures and other subject-specific information (e.g., genotype) as covariates of interest in the statistical analysis.
Participants:
PhD students (medicine, neuroscience, psychology) interested in neuroimaging. No specific qualifications required but some basic knowledge of MRI, statistics (e.g., to understand GLM), and basic matlab skills would be helpful.
Language: English
Format:
Interactive teaching with illustrative examples in the morning and practical exercises in small groups in the afternoon. The course will consist of introductory lectures in the morning (3-4 lectures per day). Thereafter students will perform practical exercises on real data sets in the afternoon. Students will be required to make a written report on their SPM analyses after the course.
ECTS-credits: 3,5.
Course directors:
Hartwig Siebner (Hvidovre Hospital) in cooperation with Henrik Larsson (Glostrup Hospital) and Lars Kai Hansen (DTU)
Dates: 13-17 September 2010
Place:
Lectures – Auditorium at Hvidovre Hospital , Kettegård Allé 30, DK-2650 Hvidovre
Workshops / Practical teaching – Danish Research Centre for Magnetic Resonance (DRCMR), MR Department, Section 340, Hvidovre Hospital
Fee: Free of charge for PhD students of University of Copenhagen and DTU.
Course secretary: Susanne Steffensen, E-mail adress: , Tel: +45 3632 3331, DRCMR, MR-afdelingen, Afs. 340, Copenhagen Hvidovre Hospital, Kettegård Allé 30, DK-2650 Hvidovre
Registration deadline: 01.09.2010
Program:
| Monday 13th Sept. 2010 Basics & Preprocessing (Local coordinators: Lars G. Hanson, A. Skimminge) | |
| 9.00 - 9.45 | Physics (Lars G. Hanson, DRCMR) |
| 9.45 - 10.30 |
Physiological basis of the BOLD signal |
| 11.00 - 12.00 | Anatomy-Toolbox (Simon Eickoff, University of Aachen) |
| 12.00 - 13.00 | Pre-processing of fMRI data (Realignment, Normalisation, Smoothing, Segmentation, Slice timing (Arnold Skimminge, DRCMR) |
| 14.00 - 16.00 | Hands on “Pre-processing” (Teaching group: A. Skimminge, T. Svensgård, M. Christensen, J. Macoveanu, T. Kassuba, K. Madsen) |
| Tuesday 14th Sept. 2010 Modelling (Local coordinators: Mark Christensen, Julian Macoveanu) | |
| 9.00 - 9.45 | Blocked fMRI designs (Julian Macoveanu, DRCMR, Hvidovre Hospital) |
| 9.45 - 10.45 | General Linear Model - General introduction and specific fMRI issues (Tobias Sommer-Blöchl, University of Hamburg) |
| 11.15 - 12.00 | Event-related and mixed fMRI designs (Mark Christensen, DRCMR, Hvidovre Hospital) |
| 12.00 - 12.30 | General discussion |
| 13.30 - 16.00 | Hands on “1st level analysis” (Teaching group: T. Kassuba, T. Sommer-Blöchl, K. Madsen, A. Skimminge, M. Christensen, J. Macoveanu) |
| Wednesday 15th Sept. 2010 Statistical inferences (Local coordinator: Tanja Kassuba) | |
| 9.00 - 10.00 | 2nd level analysis (Jan Gläscher, University of Hamburg) |
| 10.00 - 10.45 | Factorial and parametric fMRI designs (Tanja Kassuba, DRCMR, Hvidovre Hospital) |
| 11.15 - 12.00 | Correction for multiple comparisons (Gesa Hartwigsen, University of Leipzig) |
| 12.00 - 12.30 | General discussion |
| 13.30 - 16.00 | Hands on “2nd level analysis” (Teaching group: T. Kassuba, J. Gläscher, G. Hartwigsen, K. Madsen, A. Skimminge, M. Christensen, J. Macoveanu) |
| Thursday 16th Sept. 2010 Statistical inferences (Local coordinators: Kristoffer Madsen, A. Skimminge) | |
| 9.00 - 9.45 | Visualization of fMRI results (RFXplot) (Jan Gläscher, University of Hamburg) |
| 9.45 - 10.30 | Physiological monitoring (Torben Lund, CFIN, Århus University) |
| 11.00 - 12.00 | Assessing the covariance components (Kristoffer Madsen, DRCMR) |
| 12.00 - 12.30 | General discussion |
| 13.30 - 16.00 | Hands on “2nd level analysis / visualization” (Teaching group: M. Christensen, J. Gläscher, G. Hartwigsen, K. Madsen, A. Skimminge, J. Macoveanu, T. Kassuba) |
| Friday 17th Sept. 2010 Brain connectivity (Local coordinator: Hartwig Siebner, Lars K. Hansen) | |
| 9.00 - 9.45 | Resting state fMRI (Egill Rostrup, MRI-Unit, Glostrup Hospital) |
| 9.45 - 10.45 | Psycho-Physiological Interaction & Dynamic Causal Modelling (Andre Marreiros, ION, University College London) |
| 11.15 - 12.00 | Combination of diffusion MRI and fMRI (Dorothe Sauer, University of Leipzig) |
| 12.00 - 12.30 | Combination of transcranial magnetic stimulation and fMRI (Hartwig Siebner, DRCMR) |
| 12.30 - 13.00 | General discussion |
| 13.30 - 16.00 | Special interest group on PPI and DCM (Teaching group: A. Marreiros, M. Christensen, J. Macovanu, G. Hartwigsen) |