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Sunday, 28 November 2010 21:37

New research project on neural mechanisms underlying pathological gambling

The Danish Council for Independent Research has granted 2.3 million Danish kroner for a project on ludomania. The project is headed by professor Hartwig R. Siebner from the DRCMR and is entitled "Neural mechanisms underlying pathological gambling: A whole brain functional MRI study in patients with Parkinson's disease treated with dopamine agonists" . The project will be performed in cooperation with the Neurological Department at Bispebjerg Hospital and DTU Informatics.

Ludomania is characterized by pathological gambling, mostly in the form of gambling for money, and have a negative impact on work and personal relationships. 7-8% of all patients with Parkinson's disease develops ludomania, when treated with dopamine agonists (DA). Game passion provoked by DA treatment provides a unique opportunity to study the increased dopaminergic stimulation by problem gambling. Functional magnetic resonance imaging (fMRI) will be used to investigate Parkinson's patients with and without gambling addiction and a corresponding healthy control group.