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William Frans Christiaan Baaré

Email

Tel.

+45 3862 6542

Position

PhD, Senior Researcher

Research Interests

Investigating the relationship between brain structure and function, physiological variables, normal and pathological behavior and cognitive function, and genetic makeup using multimodal imaging methods, behavioral assessments, and biological (genes, cortisol) measures. Study populations include healthy children, adolescents and adult subjects, as well as 22q11, schizophrenia, affective disorders, and schizophrenia and healthy twin populations.

Curriculum Vitae

Education

2013

Research Management Course, Copenhagen Business School Executive

2001

PhD. Faculty of Medicine, University Medical Center Utrecht (UMCU), Utrecht, the Netherlands

1990

Research Assistant at the Dep. of Psychiatry, UMCU, Utrecht, the Netherlands

1992

Master degree (cum laude) in experimental and biological psychology

1986

Nursing diploma

Employments

2003 - Present

Senior Researcher, DRCMR

2006 - 2010

Senior Researcher in the Center for Integrated Molecular Brain Imaging. Work was done at the DRCMR

2002 - 2003

Post-doc, BBH

2001 - 2002

Post-doc, DRCMR

1999 - 2001

Collaborating on several brain research projects at the DRCMR, and Dep. of Psychiatry, Bispebjerg Hospital (BBH)

1996 - 1997

Six months’ work visit at the McConnel Brain Imaging Center, Montréal Neurological Institute, McGill University, Montréal, Canada

1993 - 1999

Researcher, the Dep. of Psychiatry, UMCU, Utrecht, the Netherlands

1992 - 1993

Researcher, the Dep. of Psychophysiology, University of Utrecht, Utrecht, the Netherlands

1991 - 1992

Master's thesis '' Odor processing and Odor Memory ''. Dep. of Psychiatry, UMCU, Utrecht, the Netherlands

1991 - 1991

Research Assistant at the Dutch Institute for Drugs and Doping Research N.I.D.D.R.

Full CV

Publications

Friedman, B. B., Suri, S., Solé-Padullés, C., Düzel, S., Drevon, C. A., Baaré, W. F. C., Bartrés-Faz, D., Fjell, A. M., Johansen-Berg, H., Madsen, K. S., Nyberg, L., Penninx, B. W. J. H., Sexton, C., Walhovd, K. B., Zsoldos, E. & Budin-Ljøsne, I. Are People Ready for Personalized Brain Health? Perspectives of Research Participants in the Lifebrain Consortium. The Gerontologist. 2020.
WebSearch |

Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Hulme, O., Vangkilde, A., Schmock, H., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, T., Siebner, H. R. & Garrido, M. I. Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome. Schizophrenia Research. 2020.
WebSearch |

Holm, S. K., Madsen, K. S., Vestergaard, M., Born, A. P., Paulson, O. B., Siebner, H. R., Uldall, P. & Baaré, W. F. C. Previous glucocorticoid treatment in childhood and adolescence is associated with long-term differences in subcortical grey matter volume and microstructure. NeuroImage. Clinical. 23, p. 1-11, 101825. 2019.
WebSearch |

Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Olsen, L., Didriksen, M., Baaré, W. F. C., Werge, T. M., Garrido, M. I. & Siebner, H. R. Individuals with 22q11.2 deletion syndrome show intact prediction but reduced adaptation in responses to repeated sounds: Evidence from Bayesian mapping. NeuroImage. Clinical. 22, p. 101721, 101721. 2019.
WebSearch |

Madsen K. S., Jernigan T. L., Vestergaard, M., Mortensen E. L. Baaré W. F. C. Neuroticism is linked to microstructural left-right asymmetry of fronto-limbic fibre tracts in adolescents with opposite effects in boys and girls. Neuropsychologia. 2018, April 11: 114:1-10. doi: 10.1016/j.neuropsychologia.2018.04.010. [Epub ahead of print]

Walhovd, K. B., Fjell, A. M., Westerhausen, R., Nyberg, L., Ebmeier, K. P., Lindenberger, U., Bartrés-Faz, D., Baaré, W. F. C., Siebner, H. R., Henson, R., Drevon, C. A., Strømstad Knudsen, G. P., Ljøsne, I. B., Penninx, B. W. J. H., Ghisletta, P., Rogeberg, O., Tyler, L., Bertram, L. & Lifebrain Consortium.
Healthy minds 0-100 years: Optimising the use of European brain imaging cohorts ("Lifebrain"). European psychiatry : the journal of the Association of European Psychiatrists. 2018.

Macoveanu, J., Baaré, W. F. C., Madsen, K. H., Kessing, L. V., Siebner, H. R. & Vinberg, M. Risk for affective disorders is associated with greater prefrontal gray matter volumes: A prospective longitudinal study. NeuroImage: Clinical. p. 786-793. 2018.

Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Hulme, O., Vangkilde, A., Schmock, H., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, T., Siebner, H. R. & Garrido, M. I. Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome. Schizophrenia research. 2018.

Karstensen, H. G., Vestergaard, M., Baaré, W. F. C., Skimminge, A., Djurhuus, B., Ellefsen, B., Brüggemann, N., Klausen, C., Leffers, A-M., Tommerup, N. & Siebner, H. R. Congenital olfactory impairment is linked to cortical changes in prefrontal and limbic brain regions. Brain imaging and behavior. 2018.

Holm, S. K., Madsen, K. S., Vestergaard, M., Paulson, O. B., Uldall, P., Siebner, H. R., Born, A. P. & Baaré, W. F. C. Total brain, cortical and white matter volumes in children previously treated with glucocorticoids. Pediatric Research. April, 2018; 83(4):804-812. doi: 10.1038/pr.2017.312. Epub 2018 Jan 10.

Larsen, K. M., Pellegrino , G., Birknow, M. R., Kjær , T. N., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, T., Mørup, M. & Siebner, H. R. 22q11.2 Deletion Syndrome Is Associated With Impaired Auditory Steady-State Gamma Response. Schizophrenia Bulletin. 44, 2, p. 388-397, 2018.

Borgsted, C., Ozenne, B., Mc Mahon, B., Madsen, M. K., Hjordt, L. V., Hageman, I., Baaré, W. F. C., Knudsen, G. M. & Fisher, P. M. Amygdala response to emotional faces in seasonal affective disorder. Journal of Affective Disorders. 229, p. 288-295, 2018.

Mc Mahon, B., Nørgaard, M., Svarer, C., Andersen, S. B., Korsbak Madsen, M., Baaré, W. F. C., Madsen, J., Frokjaer, V. G. & Knudsen, G. M. Seasonality-resilient individuals downregulate their cerebral serotonin transporter binding in winter while 5-HT levels appear unchanged: A longitudinal combined 11C-DASB and 11C-SB207145 PET study. 2017.

Holm-Skjold, J., Baaré, W. F. C., Mogensen, J., Siebner, H. R., Jernigan, T. L. & Madsen, K. S. Development of emotional processing is linked to maturational changes in left-right cingulum asymmetry during adolescence.
1 p., 2017.

Ekstrand, A. S., Baaré, W. F. C., Holm-Skjold, J., Siebner, H. R., Jernigan, T. L. & Madsen, K. S. Maturation of major white matter tracts during childhood and adolescence: A longitudinal study with up to 11 time points.
1 p., 2017.

Baruël Johansen, L., Madsen, K. S., Andersen, K. W., Madsen, K. H., Siebner, H. R. & Baaré, W. F. C. Reduced orbitofrontal functional network centrality characterizes high neuroticism across childhood and adolescence. 2017.

Baruël Johansen, L., Ebdrup, B. H., Nielsen, M. Ø., Baandrup, L., Klærke, L., Fagerlund, B., Glenthøj, B. Y. & Baaré, W. F. C. Neuroanatomical Markers Predictive of 4 to 17 Years Outcome in Schizophrenia? 2017.

Vestergaard, M., Krøis Holm, S., Uldall, P., Siebner, H. R., Paulson, O. B., Baaré, W. F. C. & Madsen, K. S. Glucocorticoid treatment earlier in childhood and adolescence show dose-response associations with diurnal cortisol levels. Developmental Psychobiology. 59, 8, p. 1010-1020, 2017.

Nørbak-Emig, H., Pinborg, L. H., Raghava, J. M., Svarer, C., Baaré, W. F. C., Allerup, P., Friberg, L., Rostrup, E., Glenthøj, B. & Ebdrup, B. H.
Extrastriatal dopamine D2/3 receptors and cortical grey matter volumes in antipsychotic-naïve schizophrenia patients before and after initial antipsychotic treatment. The world journal of biological psychiatry. 18, 7, p. 539-549, 18 2017.

Fisher, P. M., Ozenne, B., Svarer, C., Adamsen, D., Lehel, S., Baaré, W. F. C., Jensen, P. S. & Knudsen, G. M. BDNF val66met association with serotonin transporter binding in healthy humans.
Translational psychiatry. 7, 2, s. e1029 2017.

Mc Mahon, B., Svarer, C., Andersen, S. B., Korsbak Madsen, M., Baaré, W. F. C., Madsen, J., Frøkjær, V. & Knudsen, G. M. Individuals Resilient to Seasonal Affective Disorder Downregulate their Cerebral Serotonin Transporter Binding in Winter. 2016.

Madsen, K. S., Jernigan, T. L., Reuter, C., Thompson, W. K. & Baaré, W. F. C. Developing consistency in reaction time associated with stable individual differences in motor system microstructure: A longitudinal DTI study of children and adolescents. 2016.

Larsen, K. M., Pellegrino, G., Rosgaard Birknow, M., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, T. M., Siebner, H. R. & Mørup, M. Genetic risk for schizophrenia is associated with an impaired auditory steady-state gamma response. 2016.

Fisher, P. M., Adamsen, D., Jensen, P. S., Klein, A. B., Frøkjær, V., Gillings, N., Baaré, W. F. C. & Knudsen, G. M. Genetic predictors of subcortical serotonin transporter binding in a large healthy human cohort. 2016.

Baruël Johansen, L., Madsen, K. S., Andersen, K. W., Madsen, K. H., Siebner, H. R. & Baaré, W. F. C. Reduced global efficiency and orbitofrontal centrality of the functional brain network characterizes high neuroticism in adolescence. 2016.

Baruël Johansen, L., Ebdrup, B. H., Baandrup, L., Klærke, L., Nielsen, M. Ø., Fagerlund, B., Glenthøj, B. Y. & Baaré, W. F. C. Multimodal neuroanatomical markers predictive of 7 to 16 years outcome in antipsychotic naïve, first-episode schizophrenia patients. 2016.

Baaré, W. F. C. Mapping brain dynamics to promote health and individualize treatments. 2016.

Vangkilde, A., Jepsen, J. R. M., Schmock, H., Olesen, C., Arnarsdóttir, S., Baaré, W. F. C., Plessen, K. J., Didriksen, M., Siebner, H. R., Werge, T. & Olsen, L. Associations between social cognition, skills, and function and subclinical negative and positive symptoms in 22q11.2 deletion syndrome. Journal of Neurodevelopmental Disorders. 8, 1, 13 p., 42 2016.

Macoveanu, J., Vinberg, M., Madsen, K., Kessing, L. V., Siebner, H. R. & Baaré, W. Unaffected twins discordant for affective disorders show changes in anterior callosal white matter microstructure. Acta Psychiatrica Scandinavica. 134, 5, p. 441-451, 2016.

Mc Mahon B, Andersen SB, Madsen MK, Hjordt LV, Hageman I, Dam H, et al. Seasonal difference in brain serotonin transporter binding predicts symptom severity in patients with seasonal affective disorder. Brain : a journal of neurology. 2016.

Knudsen GM, Jensen PS, Erritzoe D, Baare WF, Ettrup A, Fisher PM, et al. The Center for Integrated Molecular Brain Imaging (Cimbi) database. NeuroImage. 2016;124(Pt B):1213-9.

Angstmann S, Madsen KS, Skimminge A, Jernigan TL, Baare WF, Siebner HR. Microstructural asymmetry of the corticospinal tracts predicts right-left differences in circle drawing skill in right-handed adolescents. Brain structure & function. 2016.

Schmock H, Vangkilde A, Larsen KM, Fischer E, Birknow MR, Jepsen JR, et al. The Danish 22q11 research initiative. BMC psychiatry. 2015;15:220.

Holm SK, Vestergaard M, Madsen KS, Baare WF, Hammer TB, Born AP, et al. Children and adolescents previously treated with glucocorticoids display lower verbal intellectual abilities. Acta paediatrica (Oslo, Norway : 1992). 2015;104(8):784-91.

Haahr ME, Hansen DL, Fisher PM, Svarer C, Stenbaek DS, Madsen K, et al. Central 5-HT neurotransmission modulates weight loss following gastric bypass surgery in obese individuals. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015;35(14):5884-9.

Fisher PM, Holst KK, Adamsen D, Klein AB, Frokjaer VG, Jensen PS, et al. BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels. Human brain mapping. 2015;36(1):313-23.

Haahr ME, Fisher PM, Jensen CG, Frokjaer VG, Mahon BM, Madsen K, et al. Central 5-HT4 receptor binding as biomarker of serotonergic tonus in humans: a [11C]SB207145 PET study. Molecular psychiatry. 2014;19(4):427-32.

Greve DN, Svarer C, Fisher PM, Feng L, Hansen AE, Baare W, et al. Cortical surface-based analysis reduces bias and variance in kinetic modeling of brain PET data. NeuroImage. 2014;92:225-36.

Aarnink SH, Vos SB, Leemans A, Jernigan TL, Madsen KS, Baare WF. Automated longitudinal intra-subject analysis (ALISA) for diffusion MRI tractography. NeuroImage. 2014;86:404-16.

Nejad AB, Madsen KH, Ebdrup BH, Siebner HR, Rasmussen H, Aggernaes B, et al. Neural markers of negative symptom outcomes in distributed working memory brain activity of antipsychotic-naive schizophrenia patients. The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). 2013;16(6):1195-204.

Klarborg B, Skak Madsen K, Vestergaard M, Skimminge A, Jernigan TL, Baare WF. Sustained attention is associated with right superior longitudinal fasciculus and superior parietal white matter microstructure in children. Human brain mapping. 2013;34(12):3216-32.

Hammer TB, Oranje B, Skimminge A, Aggernaes B, Ebdrup BH, Glenthoj B, et al. Structural brain correlates of sensorimotor gating in antipsychotic-naive men with first-episode schizophrenia. Journal of psychiatry & neuroscience : JPN. 2013;38(1):34-42

Haahr ME, Fisher P, Holst K, Madsen K, Jensen CG, Marner L, et al. The 5-HT4 receptor levels in hippocampus correlates inversely with memory test performance in humans. Human brain mapping. 2013;34(11):3066-74.

Frokjaer VG, Erritzoe D, Holst KK, Jensen PS, Rasmussen PM, Fisher PM, et al. Prefrontal serotonin transporter availability is positively associated with the cortisol awakening response. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 2013;23(4):285-94.

Fagerlund B, Pinborg LH, Mortensen EL, Friberg L, Baare WF, Gade A, et al. Relationship of frontal D(2/3) binding potentials to cognition: a study of antipsychotic-naive schizophrenia patients. The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). 2013;16(1):23-36.

Ramsoy TZ, Liptrot MG, Skimminge A, Lund TE, Sidaros K, Christensen MS, et al. Healthy aging attenuates task-related specialization in the human medial temporal lobe. Neurobiology of aging. 2012;33(9):1874-89.

Marner L, Frokjaer VG, Kalbitzer J, Lehel S, Madsen K, Baare WF, et al. Loss of serotonin 2A receptors exceeds loss of serotonergic projections in early Alzheimer's disease: a combined [11C]DASB and [18F]altanserin-PET study. Neurobiology of aging. 2012;33(3):479-87.

Madsen KS, Jernigan TL, Iversen P, Frokjaer VG, Mortensen EL, Knudsen GM, et al. Cortisol awakening response and negative emotionality linked to asymmetry in major limbic fibre bundle architecture. Psychiatry research. 2012;201(1):63-72.

Madsen KS, Jernigan TL, Iversen P, Frokjaer VG, Knudsen GM, Siebner HR, et al. Hypothalamic-pituitary-adrenal axis tonus is associated with hippocampal microstructural asymmetry. NeuroImage. 2012;63(1):95-103.

Haahr ME, Rasmussen PM, Madsen K, Marner L, Ratner C, Gillings N, et al. Obesity is associated with high serotonin 4 receptor availability in the brain reward circuitry. NeuroImage. 2012;61(4):884-8.

Fisher PM, Holst KK, Mc Mahon B, Haahr ME, Madsen K, Gillings N, et al. 5-HTTLPR status predictive of neocortical 5-HT4 binding assessed with [(11)C]SB207145 PET in humans. NeuroImage. 2012;62(1):130-6.

Vestergaard M, Madsen KS, Baare WF, Skimminge A, Ejersbo LR, Ramsoy TZ, et al. White matter microstructure in superior longitudinal fasciculus associated with spatial working memory performance in children. Journal of cognitive neuroscience. 2011;23(9):2135-46.

Rasmussen H, Ebdrup BH, Erritzoe D, Aggernaes B, Oranje B, Kalbitzer J, et al. Serotonin2A receptor blockade and clinical effect in first-episode schizophrenia patients treated with quetiapine. Psychopharmacology. 2011;213(2-3):583-92.

Nejad AB, Ebdrup BH, Siebner HR, Rasmussen H, Aggernaes B, Glenthoj BY, et al. Impaired temporoparietal deactivation with working memory load in antipsychotic-naive patients with first-episode schizophrenia. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. 2011;12(4):271-81.

Marner L, Knudsen GM, Madsen K, Holm S, Baare W, Hasselbalch SG. The reduction of baseline serotonin 2A receptors in mild cognitive impairment is stable at two-year follow-up. Journal of Alzheimer's disease : JAD. 2011;23(3):453-9.

Madsen KS, Baare WF, Skimminge A, Vestergaard M, Siebner HR, Jernigan TL. Brain microstructural correlates of visuospatial choice reaction time in children. NeuroImage. 2011;58(4):1090-100.

Madsen K, Haahr MT, Marner L, Keller SH, Baare WF, Svarer C, et al. Age and sex effects on 5-HT(4) receptors in the human brain: a [(11)C]SB207145 PET study. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2011;31(6):1475-81.

Madsen K, Erritzoe D, Mortensen EL, Gade A, Madsen J, Baare W, et al. Cognitive function is related to fronto-striatal serotonin transporter levels--a brain PET study in young healthy subjects. Psychopharmacology. 2011;213(2-3):573-81.

Jernigan TL, Baare WF, Stiles J, Madsen KS. Postnatal brain development: structural imaging of dynamic neurodevelopmental processes. Progress in brain research. 2011;189:77-92.

Frederiksen KS, Garde E, Skimminge A, Ryberg C, Rostrup E, Baare WF, et al. Corpus callosum atrophy in patients with mild Alzheimer's disease. Neuro-degenerative diseases. 2011;8(6):476-82.

Ebdrup BH, Skimminge A, Rasmussen H, Aggernaes B, Oranje B, Lublin H, et al. Progressive striatal and hippocampal volume loss in initially antipsychotic-naive, first-episode schizophrenia patients treated with quetiapine: relationship to dose and symptoms. The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). 2011;14(1):69-82.

Dyrby TB, Baare WF, Alexander DC, Jelsing J, Garde E, Sogaard LV. An ex vivo imaging pipeline for producing high-quality and high-resolution diffusion-weighted imaging datasets. Human brain mapping. 2011;32(4):544-63.

Rasmussen H, Erritzoe D, Andersen R, Ebdrup BH, Aggernaes B, Oranje B, et al. Decreased frontal serotonin2A receptor binding in antipsychotic-naive patients with first-episode schizophrenia. Archives of general psychiatry. 2010;67(1):9-16.

Marner L, Gillings N, Madsen K, Erritzoe D, Baare WF, Svarer C, et al. Brain imaging of serotonin 4 receptors in humans with [11C]SB207145-PET. NeuroImage. 2010;50(3):855-61.

Madsen KS, Baare WF, Vestergaard M, Skimminge A, Ejersbo LR, Ramsoy TZ, et al. Response inhibition is associated with white matter microstructure in children. Neuropsychologia. 2010;48(4):854-62.

Klein AB, Trajkovska V, Erritzoe D, Haugbol S, Madsen J, Baare W, et al. Cerebral 5-HT2A receptor and serotonin transporter binding in humans are not affected by the val66met BDNF polymorphism status or blood BDNF levels. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2010;30(11):e1-7.

Frokjaer VG, Vinberg M, Erritzoe D, Baare W, Holst KK, Mortensen EL, et al. Familial risk for mood disorder and the personality risk factor, neuroticism, interact in their association with frontolimbic serotonin 2A receptor binding. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2010;35(5):1129-37.

Ebdrup BH, Glenthoj B, Rasmussen H, Aggernaes B, Langkilde AR, Paulson OB, et al. Hippocampal and caudate volume reductions in antipsychotic-naive first-episode schizophrenia. Journal of psychiatry & neuroscience : JPN. 2010;35(2):95-104.

Baare WF, Vinberg M, Knudsen GM, Paulson OB, Langkilde AR, Jernigan TL, et al. Hippocampal volume changes in healthy subjects at risk of unipolar depression. Journal of psychiatric research. 2010;44(10):655-62.

Ramsoy TZ, Liptrot MG, Skimminge A, Lund TE, Sidaros K, Christensen MS, et al. Regional activation of the human medial temporal lobe during intentional encoding of objects and positions. NeuroImage. 2009;47(4):1863-72.

Marner L, Knudsen GM, Haugbol S, Holm S, Baare W, Hasselbalch SG. Longitudinal assessment of cerebral 5-HT2A receptors in healthy elderly volunteers: an [18F]-altanserin PET study. European journal of nuclear medicine and molecular imaging. 2009;36(2):287-93.

Marner L, Gillings N, Comley RA, Baare WF, Rabiner EA, Wilson AA, et al. Kinetic modeling of 11C-SB207145 binding to 5-HT4 receptors in the human brain in vivo. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2009;50(6):900-8.

Kalbitzer J, Svarer C, Frokjaer VG, Erritzoe D, Baare WF, Madsen J, et al. A probabilistic approach to delineating functional brain regions. Journal of nuclear medicine technology. 2009;37(2):91-5.

Kalbitzer J, Frokjaer VG, Erritzoe D, Svarer C, Cumming P, Nielsen FA, et al. The personality trait openness is related to cerebral 5-HTT levels. NeuroImage. 2009;45(2):280-5.

Frokjaer VG, Vinberg M, Erritzoe D, Svarer C, Baare W, Budtz-Joergensen E, et al. High familial risk for mood disorder is associated with low dorsolateral prefrontal cortex serotonin transporter binding. NeuroImage. 2009;46(2):360-6.

Erritzoe D, Frokjaer VG, Haugbol S, Marner L, Svarer C, Holst K, et al. Brain serotonin 2A receptor binding: relations to body mass index, tobacco and alcohol use. NeuroImage. 2009;46(1):23-30.

Erritzoe D, Rasmussen H, Kristiansen KT, Frokjaer VG, Haugbol S, Pinborg L, et al. Cortical and subcortical 5-HT2A receptor binding in neuroleptic-naive first-episode schizophrenic patients. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2008;33(10):2435-41.

Dyrby TB, Rostrup E, Baare WF, van Straaten EC, Barkhof F, Vrenken H, et al. Segmentation of age-related white matter changes in a clinical multi-center study. NeuroImage. 2008;41(2):335-45.

Rowe JB, Sakai K, Lund TE, Ramsoy T, Christensen MS, Baare WF, et al. Is the prefrontal cortex necessary for establishing cognitive sets? The Journal of neuroscience : the official journal of the Society for Neuroscience. 2007;27(48):13303-10.

Pagsberg AK, Baare WF, Raabjerg Christensen AM, Fagerlund B, Hansen MB, Labianca J, et al. Structural brain abnormalities in early onset first-episode psychosis. Journal of neural transmission (Vienna, Austria : 1996). 2007;114(4):489-98.

Glenthoj A, Glenthoj BY, Mackeprang T, Pagsberg AK, Hemmingsen RP, Jernigan TL, et al. Basal ganglia volumes in drug-naive first-episode schizophrenia patients before and after short-term treatment with either a typical or an atypical antipsychotic drug. Psychiatry research. 2007;154(3):199-208.

Dyrby TB, Sogaard LV, Parker GJ, Alexander DC, Lind NM, Baare WF, et al. Validation of in vitro probabilistic tractography. NeuroImage. 2007;37(4):1267-77.

Hulshoff Pol HE, Schnack HG, Posthuma D, Mandl RC, Baare WF, van Oel C, et al. Genetic contributions to human brain morphology and intelligence. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2006;26(40):10235-42.

Hulshoff Pol HE, Schnack HG, Mandl RC, Brans RG, van Haren NE, Baare WF, et al. Gray and white matter density changes in monozygotic and same-sex dizygotic twins discordant for schizophrenia using voxel-based morphometry. NeuroImage. 2006;31(2):482-8.

Glenthoj BY, Mackeprang T, Svarer C, Rasmussen H, Pinborg LH, Friberg L, et al. Frontal dopamine D(2/3) receptor binding in drug-naive first-episode schizophrenic patients correlates with positive psychotic symptoms and gender. Biological psychiatry. 2006;60(6):621-9.

Hulshoff Pol HE, Brans RG, van Haren NE, Schnack HG, Langen M, Baare WF, et al. Gray and white matter volume abnormalities in monozygotic and same-gender dizygotic twins discordant for schizophrenia. Biological psychiatry. 2004;55(2):126-30.

Posthuma D, Baare WF, Hulshoff Pol HE, Kahn RS, Boomsma DI, De Geus EJ. Genetic correlations between brain volumes and the WAIS-III dimensions of verbal comprehension, working memory, perceptual organization, and processing speed. Twin research : the official journal of the International Society for Twin Studies. 2003;6(2):131-9.

Posthuma D, De Geus EJ, Baare WF, Hulshoff Pol HE, Kahn RS, Boomsma DI. The association between brain volume and intelligence is of genetic origin. Nature neuroscience. 2002;5(2):83-4.

Hulshoff Pol HE, Schnack HG, Bertens MG, van Haren NE, van der Tweel I, Staal WG, et al. Volume changes in gray matter in patients with schizophrenia. The American journal of psychiatry. 2002;159(2):244-50.

Hulshoff Pol HE, Posthuma D, Baare WF, De Geus EJ, Schnack HG, van Haren NE, et al. Twin-singleton differences in brain structure using structural equation modelling. Brain : a journal of neurology. 2002;125(Pt 2):384-90.

van Oel CJ, Baare WF, Hulshoff Pol HE, Haag J, Balazs J, Dingemans A, et al. Differentiating between low and high susceptibility to schizophrenia in twins: the significance of dermatoglyphic indices in relation to other determinants of brain development. Schizophrenia research. 2001;52(3):181-93.

Schnack HG, Hulshoff Pol HE, Baare WF, Viergever MA, Kahn RS. Automatic segmentation of the ventricular system from MR images of the human brain. NeuroImage. 2001;14(1 Pt 1):95-104.

Schnack HG, Hulshoff Pol HE, Baare WF, Staal WG, Viergever MA, Kahn RS. Automated separation of gray and white matter from MR images of the human brain. NeuroImage. 2001;13(1):230-7.

Baare WF, van Oel CJ, Hulshoff Pol HE, Schnack HG, Durston S, Sitskoorn MM, et al. Volumes of brain structures in twins discordant for schizophrenia. Archives of general psychiatry. 2001;58(1):33-40.

Baare WF, Hulshoff Pol HE, Boomsma DI, Posthuma D, de Geus EJ, Schnack HG, et al. Quantitative genetic modeling of variation in human brain morphology. Cerebral cortex (New York, NY : 1991). 2001;11(9):816-24.

Posthuma D, de Geus EJ, Neale MC, Hulshoff Pol HE, Baare WEC, Kahn RS, et al. Multivariate genetic analysis of brain structure in an extended twin design. Behavior genetics. 2000;30(4):311-9.

Le Goualher G, Argenti AM, Duyme M, Baare WF, Hulshoff Pol HE, Boomsma DI, et al. Statistical sulcal shape comparisons: application to the detection of genetic encoding of the central sulcus shape. NeuroImage. 2000;11(5 Pt 1):564-74.

Hulshoff Pol HE, Hijman R, Baare WF, van Eekelen S, van Ree JM. Odor discrimination and task duration in young and older adults. Chemical senses. 2000;25(4):461-4.

Baare WF, Hulshoff Pol HE, Hijman R, Mali WP, Viergever MA, Kahn RS. Volumetric analysis of frontal lobe regions in schizophrenia: relation to cognitive function and symptomatology. Biological psychiatry. 1999;45(12):1597-605.

Hulshoff Pol HE, Hijman R, Baare WF, van Ree JM. Effects of context on judgements of odor intensities in humans. Chemical senses. 1998;23(2):131-5.

Hulshoff Pol HE, Baare WF, Mali WP, van Ree JM, Kahn RS. [Schizophrenia in clinical imaging; anomalies in brain anatomy and metabolism]. Nederlands tijdschrift voor geneeskunde. 1995;139(10):494-7.

Haahr ME, Fisher P, Holst K, Madsen K, Jensen CG, Marner L, et al. The 5-HT4 receptor levels in hippocampus correlates inversely with memory test performance in humans. Human brain mapping. 2013;34(11):3066-74.

Frokjaer VG, Erritzoe D, Holst KK, Jensen PS, Rasmussen PM, Fisher PM, et al. Prefrontal serotonin transporter availability is positively associated with the cortisol awakening response. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 2013;23(4):285-94.

Fagerlund B, Pinborg LH, Mortensen EL, Friberg L, Baare WF, Gade A, et al. Relationship of frontal D(2/3) binding potentials to cognition: a study of antipsychotic-naive schizophrenia patients. The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). 2013;16(1):23-36.

Ramsoy TZ, Liptrot MG, Skimminge A, Lund TE, Sidaros K, Christensen MS, et al. Healthy aging attenuates task-related specialization in the human medial temporal lobe. Neurobiology of aging. 2012;33(9):1874-89.

Marner L, Frokjaer VG, Kalbitzer J, Lehel S, Madsen K, Baare WF, et al. Loss of serotonin 2A receptors exceeds loss of serotonergic projections in early Alzheimer's disease: a combined [11C]DASB and [18F]altanserin-PET study. Neurobiology of aging. 2012;33(3):479-87.

Madsen KS, Jernigan TL, Iversen P, Frokjaer VG, Mortensen EL, Knudsen GM, et al. Cortisol awakening response and negative emotionality linked to asymmetry in major limbic fibre bundle architecture. Psychiatry research. 2012;201(1):63-72.

Madsen KS, Jernigan TL, Iversen P, Frokjaer VG, Knudsen GM, Siebner HR, et al. Hypothalamic-pituitary-adrenal axis tonus is associated with hippocampal microstructural asymmetry. NeuroImage. 2012;63(1):95-103.

Haahr ME, Rasmussen PM, Madsen K, Marner L, Ratner C, Gillings N, et al. Obesity is associated with high serotonin 4 receptor availability in the brain reward circuitry. NeuroImage. 2012;61(4):884-8.

Fisher PM, Holst KK, Mc Mahon B, Haahr ME, Madsen K, Gillings N, et al. 5-HTTLPR status predictive of neocortical 5-HT4 binding assessed with [(11)C]SB207145 PET in humans. NeuroImage. 2012;62(1):130-6.

Vestergaard M, Madsen KS, Baare WF, Skimminge A, Ejersbo LR, Ramsoy TZ, et al. White matter microstructure in superior longitudinal fasciculus associated with spatial working memory performance in children. Journal of cognitive neuroscience. 2011;23(9):2135-46.

Rasmussen H, Ebdrup BH, Erritzoe D, Aggernaes B, Oranje B, Kalbitzer J, et al. Serotonin2A receptor blockade and clinical effect in first-episode schizophrenia patients treated with quetiapine. Psychopharmacology. 2011;213(2-3):583-92.

Nejad AB, Ebdrup BH, Siebner HR, Rasmussen H, Aggernaes B, Glenthoj BY, et al. Impaired temporoparietal deactivation with working memory load in antipsychotic-naive patients with first-episode schizophrenia. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. 2011;12(4):271-81.

Marner L, Knudsen GM, Madsen K, Holm S, Baare W, Hasselbalch SG. The reduction of baseline serotonin 2A receptors in mild cognitive impairment is stable at two-year follow-up. Journal of Alzheimer's disease : JAD. 2011;23(3):453-9.

Madsen KS, Baare WF, Skimminge A, Vestergaard M, Siebner HR, Jernigan TL. Brain microstructural correlates of visuospatial choice reaction time in children. NeuroImage. 2011;58(4):1090-100.

Madsen K, Haahr MT, Marner L, Keller SH, Baare WF, Svarer C, et al. Age and sex effects on 5-HT(4) receptors in the human brain: a [(11)C]SB207145 PET study. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2011;31(6):1475-81.

Madsen K, Erritzoe D, Mortensen EL, Gade A, Madsen J, Baare W, et al. Cognitive function is related to fronto-striatal serotonin transporter levels--a brain PET study in young healthy subjects. Psychopharmacology. 2011;213(2-3):573-81.

Jernigan TL, Baare WF, Stiles J, Madsen KS. Postnatal brain development: structural imaging of dynamic neurodevelopmental processes. Progress in brain research. 2011;189:77-92.

Frederiksen KS, Garde E, Skimminge A, Ryberg C, Rostrup E, Baare WF, et al. Corpus callosum atrophy in patients with mild Alzheimer's disease. Neuro-degenerative diseases. 2011;8(6):476-82.

Ebdrup BH, Skimminge A, Rasmussen H, Aggernaes B, Oranje B, Lublin H, et al. Progressive striatal and hippocampal volume loss in initially antipsychotic-naive, first-episode schizophrenia patients treated with quetiapine: relationship to dose and symptoms. The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). 2011;14(1):69-82.

Dyrby TB, Baare WF, Alexander DC, Jelsing J, Garde E, Sogaard LV. An ex vivo imaging pipeline for producing high-quality and high-resolution diffusion-weighted imaging datasets. Human brain mapping. 2011;32(4):544-63.

Rasmussen H, Erritzoe D, Andersen R, Ebdrup BH, Aggernaes B, Oranje B, et al. Decreased frontal serotonin2A receptor binding in antipsychotic-naive patients with first-episode schizophrenia. Archives of general psychiatry. 2010;67(1):9-16.

Marner L, Gillings N, Madsen K, Erritzoe D, Baare WF, Svarer C, et al. Brain imaging of serotonin 4 receptors in humans with [11C]SB207145-PET. NeuroImage. 2010;50(3):855-61.

Madsen KS, Baare WF, Vestergaard M, Skimminge A, Ejersbo LR, Ramsoy TZ, et al. Response inhibition is associated with white matter microstructure in children. Neuropsychologia. 2010;48(4):854-62.

Klein AB, Trajkovska V, Erritzoe D, Haugbol S, Madsen J, Baare W, et al. Cerebral 5-HT2A receptor and serotonin transporter binding in humans are not affected by the val66met BDNF polymorphism status or blood BDNF levels. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2010;30(11):e1-7.

Frokjaer VG, Vinberg M, Erritzoe D, Baare W, Holst KK, Mortensen EL, et al. Familial risk for mood disorder and the personality risk factor, neuroticism, interact in their association with frontolimbic serotonin 2A receptor binding. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2010;35(5):1129-37.

Ebdrup BH, Glenthoj B, Rasmussen H, Aggernaes B, Langkilde AR, Paulson OB, et al. Hippocampal and caudate volume reductions in antipsychotic-naive first-episode schizophrenia. Journal of psychiatry & neuroscience : JPN. 2010;35(2):95-104.

Baare WF, Vinberg M, Knudsen GM, Paulson OB, Langkilde AR, Jernigan TL, et al. Hippocampal volume changes in healthy subjects at risk of unipolar depression. Journal of psychiatric research. 2010;44(10):655-62.

Ramsoy TZ, Liptrot MG, Skimminge A, Lund TE, Sidaros K, Christensen MS, et al. Regional activation of the human medial temporal lobe during intentional encoding of objects and positions. NeuroImage. 2009;47(4):1863-72.

Marner L, Knudsen GM, Haugbol S, Holm S, Baare W, Hasselbalch SG. Longitudinal assessment of cerebral 5-HT2A receptors in healthy elderly volunteers: an [18F]-altanserin PET study. European journal of nuclear medicine and molecular imaging. 2009;36(2):287-93.

Marner L, Gillings N, Comley RA, Baare WF, Rabiner EA, Wilson AA, et al. Kinetic modeling of 11C-SB207145 binding to 5-HT4 receptors in the human brain in vivo. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2009;50(6):900-8.

Kalbitzer J, Svarer C, Frokjaer VG, Erritzoe D, Baare WF, Madsen J, et al. A probabilistic approach to delineating functional brain regions. Journal of nuclear medicine technology. 2009;37(2):91-5.

Kalbitzer J, Frokjaer VG, Erritzoe D, Svarer C, Cumming P, Nielsen FA, et al. The personality trait openness is related to cerebral 5-HTT levels. NeuroImage. 2009;45(2):280-5.

Frokjaer VG, Vinberg M, Erritzoe D, Svarer C, Baare W, Budtz-Joergensen E, et al. High familial risk for mood disorder is associated with low dorsolateral prefrontal cortex serotonin transporter binding. NeuroImage. 2009;46(2):360-6.

Erritzoe D, Frokjaer VG, Haugbol S, Marner L, Svarer C, Holst K, et al. Brain serotonin 2A receptor binding: relations to body mass index, tobacco and alcohol use. NeuroImage. 2009;46(1):23-30.

Erritzoe D, Rasmussen H, Kristiansen KT, Frokjaer VG, Haugbol S, Pinborg L, et al. Cortical and subcortical 5-HT2A receptor binding in neuroleptic-naive first-episode schizophrenic patients. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2008;33(10):2435-41.

Dyrby TB, Rostrup E, Baare WF, van Straaten EC, Barkhof F, Vrenken H, et al. Segmentation of age-related white matter changes in a clinical multi-center study. NeuroImage. 2008;41(2):335-45.

Rowe JB, Sakai K, Lund TE, Ramsoy T, Christensen MS, Baare WF, et al. Is the prefrontal cortex necessary for establishing cognitive sets? The Journal of neuroscience : the official journal of the Society for Neuroscience. 2007;27(48):13303-10.

Pagsberg AK, Baare WF, Raabjerg Christensen AM, Fagerlund B, Hansen MB, Labianca J, et al. Structural brain abnormalities in early onset first-episode psychosis. Journal of neural transmission (Vienna, Austria : 1996). 2007;114(4):489-98.

Glenthoj A, Glenthoj BY, Mackeprang T, Pagsberg AK, Hemmingsen RP, Jernigan TL, et al. Basal ganglia volumes in drug-naive first-episode schizophrenia patients before and after short-term treatment with either a typical or an atypical antipsychotic drug. Psychiatry research. 2007;154(3):199-208.

Dyrby TB, Sogaard LV, Parker GJ, Alexander DC, Lind NM, Baare WF, et al. Validation of in vitro probabilistic tractography. NeuroImage. 2007;37(4):1267-77.

Hulshoff Pol HE, Schnack HG, Posthuma D, Mandl RC, Baare WF, van Oel C, et al. Genetic contributions to human brain morphology and intelligence. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2006;26(40):10235-42.

Hulshoff Pol HE, Schnack HG, Mandl RC, Brans RG, van Haren NE, Baare WF, et al. Gray and white matter density changes in monozygotic and same-sex dizygotic twins discordant for schizophrenia using voxel-based morphometry. NeuroImage. 2006;31(2):482-8.

Glenthoj BY, Mackeprang T, Svarer C, Rasmussen H, Pinborg LH, Friberg L, et al. Frontal dopamine D(2/3) receptor binding in drug-naive first-episode schizophrenic patients correlates with positive psychotic symptoms and gender. Biological psychiatry. 2006;60(6):621-9.

Hulshoff Pol HE, Brans RG, van Haren NE, Schnack HG, Langen M, Baare WF, et al. Gray and white matter volume abnormalities in monozygotic and same-gender dizygotic twins discordant for schizophrenia. Biological psychiatry. 2004;55(2):126-30.

Posthuma D, Baare WF, Hulshoff Pol HE, Kahn RS, Boomsma DI, De Geus EJ. Genetic correlations between brain volumes and the WAIS-III dimensions of verbal comprehension, working memory, perceptual organization, and processing speed. Twin research : the official journal of the International Society for Twin Studies. 2003;6(2):131-9.

Posthuma D, De Geus EJ, Baare WF, Hulshoff Pol HE, Kahn RS, Boomsma DI. The association between brain volume and intelligence is of genetic origin. Nature neuroscience. 2002;5(2):83-4.

Hulshoff Pol HE, Schnack HG, Bertens MG, van Haren NE, van der Tweel I, Staal WG, et al. Volume changes in gray matter in patients with schizophrenia. The American journal of psychiatry. 2002;159(2):244-50.

Hulshoff Pol HE, Posthuma D, Baare WF, De Geus EJ, Schnack HG, van Haren NE, et al.Twin-singleton differences in brain structure using structural equation modelling. Brain : a journal of neurology. 2002;125(Pt 2):384-90.

van Oel CJ, Baare WF, Hulshoff Pol HE, Haag J, Balazs J, Dingemans A, et al. Differentiating between low and high susceptibility to schizophrenia in twins: the significance of dermatoglyphic indices in relation to other determinants of brain development. Schizophrenia research. 2001;52(3):181-93.

Schnack HG, Hulshoff Pol HE, Baare WF, Viergever MA, Kahn RS. Automatic segmentation of the ventricular system from MR images of the human brain. NeuroImage. 2001;14(1 Pt 1):95-104.

Schnack HG, Hulshoff Pol HE, Baare WF, Staal WG, Viergever MA, Kahn RS. Automated separation of gray and white matter from MR images of the human brain. NeuroImage. 2001;13(1):230-7.

Baare WF, van Oel CJ, Hulshoff Pol HE, Schnack HG, Durston S, Sitskoorn MM, et al. Volumes of brain structures in twins discordant for schizophrenia. Archives of general psychiatry. 2001;58(1):33-40.

Baare WF, Hulshoff Pol HE, Boomsma DI, Posthuma D, de Geus EJ, Schnack HG, et al. Quantitative genetic modeling of variation in human brain morphology. Cerebral cortex (New York, NY : 1991). 2001;11(9):816-24.

Posthuma D, de Geus EJ, Neale MC, Hulshoff Pol HE, Baare WEC, Kahn RS, et al. Multivariate genetic analysis of brain structure in an extended twin design. Behavior genetics. 2000;30(4):311-9.

Le Goualher G, Argenti AM, Duyme M, Baare WF, Hulshoff Pol HE, Boomsma DI, et alStatistical sulcal shape comparisons: application to the detection of genetic encoding of the central sulcus shape. NeuroImage. 2000;11(5 Pt 1):564-74.

Hulshoff Pol HE, Hijman R, Baare WF, van Eekelen S, van Ree JM. Odor discrimination and task duration in young and older adults. Chemical senses. 2000;25(4):461-4.

Baare WF, Hulshoff Pol HE, Hijman R, Mali WP, Viergever MA, Kahn RS. Volumetric analysis of frontal lobe regions in schizophrenia: relation to cognitive function and symptomatology. Biological psychiatry. 1999;45(12):1597-605.

Hulshoff Pol HE, Hijman R, Baare WF, van Ree JM. Effects of context on judgements of odor intensities in humans. Chemical senses. 1998;23(2):131-5.

Hulshoff Pol HE, Baare WF, Mali WP, van Ree JM, Kahn RS. [Schizophrenia in clinical imaging; anomalies in brain anatomy and metabolism]. Nederlands tijdschrift voor geneeskunde. 1995;139(10):494-7.