To test new models, e.g. various fibre reconstruction methods, high-quality diffusion MRI data sets acquired with multiple b-values is a must. This ex vivo diffusion MRI data set consists of multiple b-values acquired within the same scanning session and, since motion during scanning is absent, the dataset allows voxel-to-voxel comparison across b-values directly on the acquired dataset.

Facts about the dataset:

Sequence: diffusion weighted pulse gradient spin echo (PGSE) with single line readout. Image matrix: 128x64, Voxel size: 0.51x0.51x0.5 mm^3, slices: 5, TR= 2500 ms, TE=67.8ms and NEX=4 (averaged off line). Diffusion weighted gradient strength (Gmax)* has been increased in steps of [29, 44, 49, 56, 68, 80, 111] mT/m, small delta: 27 ms, big delta: 33.5 ms, producing b-values of [1018, 2475, 3069, 4009, 5911, 8181,11295, 15750] s/mm^2  

To cite: 

Dyrby TB, Baaré WF, Alexander DC, Jelsing J, Garde E, Søgaard LV, An ex vivo imaging pipeline for producing high-quality and high-resolution diffusion weighted imaging datasets, Human Brain mapping, April,2011

Download the multiple-bvalue dataset here 

Observed problems or artifacts: Please note that the data set only contain 4 axial slices of a half pig brain and that there is a gab between slices. We have observed minor motion but have not aligned the data set before off line averaging (NEX4) due to this gab.  

Funding:

The Lundbeck Foundation and the Velux Foundation