Acquisition Technology

 Some of the activities in the Acquisition Technology group involves development of hardware. The image shows unique electronics developed by Christian G. Hanson for real-time processing of signals acquired during MRI. This was recently used for sensing and encoding k-space trajectories in MR raw data.


Focus area:

  • Motion and artifacts
  • Multi-modal data acquisition 
  • Spectroscopy and spectroscopic imaging
  • Fundamentals and education

The members of the Acquisition Technology at the DRCMR and DTU do research improving MR scanning, e.g. with respect to speed, robustness, sensitivity or specificity. They also work on separate topics in other research groups. The employed methods range from fundamental physics to advanced data processing techniques needed to extract important physiological parameters from the measurements. The targets of the development include imaging, spectroscopy, and multi-modal acquisition. This benefits, for example, the departments neurophysics and highfield research. 

The group also contributes to research projects, e.g., concerning sequence choices and sensitivity consideration, and provide education in MRI physics and techniques at the DRCMR, the DTU and elsewhere. Educational material and software is made freely available, and is used widely internationally.


Selected Publications

J. O. Pedersen, C. G. Hanson, R. Xue & L. G. Hanson Inductive measurement and encoding of k-space trajectories in MR raw data, Magn Reson Mater Phy, preprint, 2019.

R. B. Hansen, J. D. Sánchez-Heredia, N. Bøgh, E. S. S. Hansen, C. Laustsen, L. G. Hanson & J. H. Ardenkjær-Larsen. Coil profile estimation strategies for parallel imaging with hyperpolarized 13 C MRI, Magn Reson Med, DOI: 10.1002/mrm.27892, 2019.

Göksu, C., Scheffler K., Siebner H. R., Thielscher, A., & Hanson, L.G. The stray magnetic fields in Magnetic Resonance Current Density Imaging (MRCDI), Phys Med 59, 142-150, 2019.

Magnusson, P., Boer, V., Marsman, A., Paulson, O. B., Hanson, L. G. & Petersen, E. T. Gamma-aminobutyric acid edited echo-planar spectroscopic imaging (EPSI) with MEGA-sLASER at 7T, Magn Reson Med, 81(2), p. 773-780, 2019.

Pedersen, J. O. Encoding of non-MR signals in Magnetic Resonance Imaging data. PhD thesis, Technical University of Denmark, Electrical Engineering, 2018.

Pedersen, J. O., Hanson, C. G., Xue, R.  & Hanson, L. G. General Purpose Electronics for Real-Time Processing and encoding of non-MR Data in MR Acquisitions, Concepts in Magn Reson B, 48B(2), e21385, 2018.

Eldirdiri, A., Posse, S., Hanson, L. G., Hansen, R. B., Holst, P., Schøier, C., Kristensen, A. T., Johannesen, H. H., Kjaer, A., Hansen, A. E.  & Ardenkjær-Larsen, J. H. Development of a Symmetric Echo Planar Spectroscopic Imaging Framework for Hyperpolarized 13C Imaging in a Clinical PET/MR Scanner, Tomography, 4(3), p. 110-22, 20184(3), p. 110-22, 2018.

Wilhjelm J. E., Duun-Henriksen J. & Hanson L. G., A virtual scanner for teaching fundamental magnetic resonance in biomedical engineering, Comput Appl Eng Educ, 26(6), p. 2197-2209, 2018

Göksu, C., Hanson, L. G., Siebner, H. R., Ehses, P., Scheffler, K. & Thielscher, A. Human in-vivo brain magnetic resonance current density imaging (MRCDI). NeuroImage. 171, p. 26-39, 2018.

Göksu C, Scheffler K, Ehses P, Hanson L.G & Thielscher A. Sensitivity Analysis of Magnetic Field Measurements for Magnetic Resonance Electrical Impedance Tomography (MREIT), Magnetic Resonance in Medicine. 79, p. 748-760, 2018.

Laustsen, M., Andersen, M., Lehmann, P. M., Xue, R., Madsen, K. H. & Hanson, L. G. Slice-wise motion tracking during simultaneous EEG-fMRI. Joint Annual Meeting ISMRM-ESMRMB 2018.

Petersen, J. R., Pedersen, J. O., Zhurbenko, V., Ardenkjær-Larsen, J. H. & Hanson, L. G. Ultra-low power transmitter for encoding non-MR signals in Magnetic Resonance  recordings. Joint Annual Meeting ISMRM-ESMRMB 2018.

Göksu, C., Hanson, L. G., Siebner, H. R., Ehses, P., Scheffler, K. & Thielscher, A. Comparison of two alternative sequences for human in-vivo brain MR Current Density Imaging (MRCDI). Joint Annual Meeting ISMRM-ESMRMB 2018.

Göksu, C., Hanson, L. G., Siebner, H. R., Ehses, P., Scheffler, K. & Thielscher, A. Human In-vivo Brain MR Current Density Imaging (MRCDI) based on Steady-state Free Precession Free Induction Decay (SSFP-FID). Joint Annual Meeting ISMRM-ESMRMB 2018.

Andersen, M., Hanson, L. G., Madsen, K. H., Wezel, J., Boer, V., van der Velden, T., van Osch, M. J. P., Klomp, D., Webb, A. G. & Versluis, M. J. Measuring motion-induced B0 -fluctuations in the brain using field probes. Magnetic Resonance in Medicine, 75(5):2020-30, 2016.

Andersen, M., Towards Motion-Insensitive Magnetic Resonance Imaging Using Dynamic Field Measurements. PhD thesis, Technical University of Denmark, Electrical Engineering. 109 p., 2016.

Hanson, L. G. The Ups and Downs of Classical and Quantum Formulations of Magnetic Resonance. Book chapter in Anthropic Awareness: The Human Aspects of Scientific Thinking in NMR Spectroscopy and Mass Spectrometry. Edited by: C Szantay, Jr. Elsevier, Chap. 3, p. 141-171, 2015.

de Nijs, R., Miranda, MJ., Hansen, LK., Hanson, LG. Motion correction of single-voxel spectroscopy by independent component analysis applied to spectra from nonanesthetized pediatric subjects. Magn Reson Med 2009, 62(5), 1147-1154.

Hanson, LG. Is quantum mechanics necessary for understanding magnetic resonance? Concepts in Magnetic Resonance Part A 2008, 32A(5), 329-340.

Hanson, LG. A graphical simulator for teaching basic and advanced MR imaging techniques. Radiographics 2007, 27(6), e27.

Hanson, LG., Lund, TE., Hanson, CG. Encoding of electrophysiology and other signals in MR images. J. Magn Reson Imaging 2007, 25(5), 1059-1066. 

Hanson, LG., Lund, TE., Hanson, CG. Encoding and transmission of signals as RF signals for detection using an MR apparatus. WO/2005/116676, PCT/DK2005/000343 2005.

Andersen, IK., Szymkowiak, A., Rasmussen, CE., Hanson, LG., Marstrand, JR., Larsson, HB. & Hansen, LK. Perfusion quantification using Gaussian process deconvolution. Magn Reson Med 2002, 48(2), 351-361.

Hanson, LG., Adalsteinsson, E., Pfefferbaum, A., Spielman, DM. Optimal voxel size for measuring global gray and white matter proton metabolite concentrations using chemical shift imaging. Magn Reson Med 2000, 44(1), 10-18.

Hanson, LG., Schaumburg, K., Paulson, OB. Reconstruction strategy for echo planar spectroscopy and its application to partially undersampled imaging. Magn Reson Med 2000, 44(3), 412-417.

News & Events

Group Members

Lars G. Hanson

Group Leader

Kristoffer Hougaard Madsen

Malte Laustsen

Frodi Gregersen

External Collaborators

DTU Center for Magnetic Resonance

Technical University of Denmark, Lyngby (DTU Health Tech) 

Institute of Biophysics

Chinese Academy of Sciences, Beijing, China

Philips Healthcare

Copenhagen, Denmark

Max Planck Institute for Biological Cybernetics

Tübingen, Germany

DTU Biomedical Engineering

Technical University of Denmark, Lyngby (DTU Elektro)

Lund University Bioimaging Centre

Lund, Sweden