Hartwig R. Siebner

Email

Tel.

+45 3862 6541

Position

Head of Research, Prof, DMSc

Affiliations

Department of Neurology, Copenhagen University Hospital Bispebjerg

Research Interests

Mapping and shaping causal dynamics in human brain networks:
My main interest is to study the causal dynamic interactions between brain regions in the human brain. I explore how these interactions support human brain function with a focus on motor control and decision-making. I combine advanced functional brain mapping techniques with interventions such as non-invasive transcranial brain stimulation (NTBS), training, or pharmacological manipulations. This "causal" research strategy allows me to identify and shape the network dynamics that determine human brain function in health and disease.

Pathogenesis and pathophysiology of brain disorders:
I use multimodal brain imaging to cast new light on the pathogenesis and pathophysiology of major brain disorders such as Parkinson ́s disease, multiple sclerosis, dystonia, Tourette syndrome, affective disorders, and schizophrenia. Adopting a pharmaco-fMRI approach, I identified an acute motor network response to levo-dopa therapy that predicted the emergence of medication-induced dyskinesia in patients with Parkinson´s disease.

Determinants of brain function and brain plasticity across the lifespan:
Another line of research is designed to identify structural or functional correlates in the brain that underlie behavioral traits and individual preferences. My neuroimaging research on handedness yielded important insights into how nature and nurture shape brain function and structure in the motor system.

Research Groups

Coordinator of the research area "Clinical Imaging"
Multiple Sclerosis (Group Leader)
Traumatic Brain Injury (Group Leader)
Motor Control (Group Leader)
Neurophysiology (Group Leader)
Movement Disorders (Group Leader)
As Head of Research, Hartwig is involved in all remaning research groups

Curriculum Vitae

Education

2000

Board Certified Neurologist

1990

Full Medical Licence

1989

Medical State Examination

1989

Study of Medicine, Med. Faculty, Johannes Gutenberg University, Mainz

1985

Study of Medicine, Med. Faculty, Saarland University, Homburg-Saar

Employments

2017 - Present

Clinical Professor with special focus on Precision Medicine, Faculty of Health and Medical Sciences, Institute of Clinical Medicine, University of Copenhagen

2009 - 2017

Full Professor for Functional Neuroimaging, Faculty of Health and Medical Sciences, University of Copenhagen

2013 - Present

Head of Research, Movement Disorders Research, Department of Neurology, Copenhagen University Hospital Bispebjerg, Denmark

2012 - Present

Head of Research, Center for Functional and Diagnostic Imaging and Research (Includes DRCMR)

2010 - 2011

Head of Department, DRCMR, Copenhagen University Hospital Hvidovre, Denmark

2008 - 2010

Consultant, DRCMR, Copenhagen University Hospital Hvidovre, Denmark

2004 - 2008

Professor for Functional Imaging, CAU, Kiel, Germany

2002 - 2008

Consultant, Dept. of Neurology, Christian-Albrechts-University (CAU), Kiel

2002 - 2002

Visiting Professor at Department of Brain Pathophysiology, Kyoto University, Japan

2000 - 2002

Post-doctoral Research Fellow at Sobell Department for Motor Neuroscience and Movement Disorders, Institute of Neurology, London, UK

1995 - 2000

Senior house officer, Dept. of Neurology, Munich University of Technology (TUM)

1992 - 1995

Senior house officer, Dept. of Neurology, St. Vinzenz-Hospital Paderborn

1990 - 1991

Medical officer, Dept. of Neurosurgery, Bundeswehrzentralkrankenhaus, Koblenz

1989 - 1990

Junior house officer (Arzt im Praktikum), Dept. of Internal Medicine, Mutterhaus Hospital, Trier, Special training in Oncology

Full CV

Publications

Kesselheim, J., Takemi, M., Karabanov, A. & Siebner, H. R.
Is there a causal link between afferent inhibition and oscillatory brain stimulation in the human sensorimotor cortex?
2018.

Stecker, M., Pasqualetti, P., Barry, R. J., Daskalakis, Z. J., Siebner, H. R. & Ziemann, U.
Reply to "is it significant?: Is it relevant?".
Clinical neurophysiology. 129, 4, p. 887-887, 2018.

Walhovd, K. B., Fjell, A. M., Westerhausen, R., Nyberg, L., Ebmeier, K. P., Lindenberger, U., Bartrés-Faz, D., Baaré, W. F. C., Siebner, H. R., Henson, R., Drevon, C. A., Strømstad Knudsen, G. P., Ljøsne, I. B., Penninx, B. W. J. H., Ghisletta, P., Rogeberg, O., Tyler, L., Bertram, L. & Lifebrain Consortium.
Healthy minds 0-100 years: Optimising the use of European brain imaging cohorts ("Lifebrain").
European psychiatry: the journal of the Association of European Psychiatrists.

Nielsen, J. D., Madsen, K. H., Puonti, O., Siebner, H. R., Bauer, C., Madsen, C. G., Saturnino, G. B. & Thielscher, A.
Automatic skull segmentation from MR images for realistic volume conductor models of the head: Assessment of the state-of-the-art.
NeuroImage. 2018.

Macoveanu, J., Baaré, W. F. C., Madsen, K. H., Kessing, L. V., Siebner, H. R. & Vinberg, M.
Risk for affective disorders is associated with greater prefrontal gray matter volumes: A prospective longitudinal study.
NeuroImage: Clinical. p. 786-793. 2018

Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Hulme, O., Vangkilde, A., Schmock, H., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, T., Siebner, H. R. & Garrido, M. I.
Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome.
Schizophrenia research. 2018.

Karstensen, H. G., Vestergaard, M., Baaré, W. F. C., Skimminge, A., Djurhuus, B., Ellefsen, B., Brüggemann, N., Klausen, C., Leffers, A-M., Tommerup, N. & Siebner, H. R.
Congenital olfactory impairment is linked to cortical changes in prefrontal and limbic brain regions.
Brain imaging and behavior. 2018.

Holm, S. K., Madsen, K. S., Vestergaard, M., Paulson, O. B., Uldall, P., Siebner, H. R., Born, A. P. & Baaré, W. F. C.
Total brain, cortical and white matter volumes in children previously treated with glucocorticoids.
Pediatric Research. 2018.

Hallsson, B. G., Siebner, H. R. & Hulme, O. J.
Fairness, fast and slow: A review of dual process models of fairness.
Neuroscience & Biobehavioral Reviews. 2018.

Dogonowski, A. M., Andersen, K. W., Sellebjerg, F., Schreiber, K., Madsen, K. H. & Siebner, H. R.
Functional neuroimaging of recovery from motor conversion disorder: A case report.
NeuroImage. 2018.

Walhovd, K. B., Fjell, A. M., Westerhausen, R., Nyberg, L., Ebmeier, K. P., Lindenberger, U., Bartrés-Faz, D., Baaré, W. F. C., Siebner, H. R., Henson, R., Drevon, C. A., Knudsen, G. P., Budin-Ljøsne, I., Penninx, B. W. J. H., Ghisletta, P., Rogeberg, O., Tyler, L., Bertram, L. & for Lifebrain Consortium.
Healthy minds from 0-100 years: Optimising the use of European brain imaging cohorts ("Lifebrain").
European psychiatry: the journal of the Association of European Psychiatrists. 47, p. 76-87, 2018.

Ponseti, J., Bruhn, D., Nolting, J., Gerwinn, H., Pohl, A., Stirn, A., Granert, O., Laufs, H., Deuschl, G., Wolff, S., Jansen, O., Siebner, H., Briken, P., Mohnke, S., Amelung, T., Kneer, J., Schiffer, B., Walter, H. & Kruger, T. H. C.
Decoding Pedophilia: Increased Anterior Insula Response to Infant Animal Pictures.
Frontiers in Human Neuroscience. 11, 645 2018.

Miskowiak, K. W., Larsen, J. E., Harmer, C. J., Siebner, H. R., Kessing, L. V., Macoveanu, J. & Vinberg, M.
Is negative self-referent bias an endophenotype for depression?: An fMRI study of emotional self-referent words in twins at high vs. low risk of depression.
Journal of Affective Disorders. 226, p. 267-273, 2018.

Larsen, K. M., Pellegrino , G., Birknow, M. R., Kjær , T. N., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, T., Mørup, M. & Siebner, H. R.
22q11.2 Deletion Syndrome Is Associated With Impaired Auditory Steady-State Gamma Response.
Schizophrenia Bulletin. 44, 2, p. 388-397, 2018.

Jimenez, S., Mordillo-Mateos, L., Dileone, M., Campolo, M., Carrasco-Lopez, C., Moitinho-Ferreira, F., Gallego-Izquierdo, T., Siebner, H. R., Valls-Solé, J., Aguilar, J. & Oliviero, A.
Effects of patterned peripheral nerve stimulation on soleus spinal motor neuron excitability.
P L o S One. 13, 2 2018.

Hjortkjær, J., Kassuba, T., Madsen, K. H., Skov, M. & Siebner, H. R.
Task-Modulated Cortical Representations of Natural Sound Source Categories.
Cerebral Cortex. 28, 1, p. 295-306, 2018.

Göksu, C., Hanson, L. G., Siebner, H. R., Ehses, P., Scheffler, K. & Thielscher, A.
Human in-vivo brain magnetic resonance current density imaging (MRCDI).
NeuroImage. 171, p. 26-39, 2018.

Gaist, D., Hougaard, A., Garde, E., Reislev, N. L., Wiwie, R., Iversen, P., Madsen, C. G., Blaabjerg, M., Nielsen, H. H., Krøigård, T., Østergaard, K., Kyvik, K. O., Hjelmborg, J., Madsen, K., Siebner, H. R. & Ashina, M.
Migraine with visual aura associated with thicker visual cortex.
Brain. 141, 3, p. 776-785, 2018.

ver Loren van Themaat, A. H., Korsgaard, L., Thorup, A. A. E., Baladi Nejad, A., Larsen, M., Vangkilde, S. A., Nordentoft, M., Oranje, B., Siebner, H. R. & Plessen , K. J.
The Danish High Risk and Resilience Study – VIA 11 – Error Monitoring in 11-Year-Old-Children of Parents with either Schizophrenia or Bipolar Disorder: an EEG study.
2017.

Skoven, C., Kvitsiani, D., Pakkenberg, B., Siebner, H. R. & Dyrby, T. B.
Illuminating the Neurobiological Mechanisms of Non-invasive Transcranial Brain Stimulation (NTBS) Techniques.
2017.

Ruiz, V. C., Tomasevic, L., Akopian, I., Stanek, K., Bergmann, T. O. & Siebner, H. R.
Contribution of integrated somatosensory and auditory inputs to the cortical response evoked by transcranial magnetic stimulation: a sham TMS-EEG study.
1 p., 2017.

Morville, T., Siebner, H. R. & Hulme, O. J.
Reward Prediction Errors and the Marginal Utility of Glucose under Fluctuating Glycemic States.
2017.

Meder, D., Kolling, N., Verhagen, L., Wittmann, M. K., Madsen, K. H., Hulme, O. J., Behrens, T. E. J., Siebner, H. R. & Rushworth, M. F.
Simultaneous Representation of a Spectrum of Dynamically Changing Value Estimates.
2017.

Holm-Skjold, J., Baaré, W. F. C., Mogensen, J., Siebner, H. R., Jernigan, T. L. & Madsen, K. S.
Development of emotional processing is linked to maturational changes in left-right cingulum asymmetry during adolescence.
1 p., 2017.

Hansen, A. L., Marsman, A., Madsen, C. D., Garde, E., Mortensen, E. L., Rasmussen, L. J., Petersen, E. T. & Siebner, H. R.
Mitochondrial and Immunological Effects on the Interplay Between Brain and Body Ageing.
2017.

Ekstrand, A. S., Baaré, W. F. C., Holm-Skjold, J., Siebner, H. R., Jernigan, T. L. & Madsen, K. S.
Maturation of major white matter tracts during childhood and adolescence: A longitudinal study with up to 11 time points.
1 p., 2017.

Baruël Johansen, L., Madsen, K. S., Andersen, K. W., Madsen, K. H., Siebner, H. R. & Baaré, W. F. C.
Reduced orbitofrontal functional network centrality characterizes high neuroticism across childhood and adolescence.
2017.

Andersen, S. H., Ruiz, V. C., Larsen, K. B., Andersen, K. W., Hvass Petersen, T., Madsen, K., Graff, J., Kammersgaard, L. P., Poulsen, I. & Siebner, H. R.
ABC in TBI (Alterations in the Brain´s Connectome during recovery from severe Traumatic Brain Injury): A critical step towards predicting and understanding recovery of consciousness.
2017.

Andersen, K. W., Madsen, K. H. & Siebner, H. R.
Rock-paper-scissors - Hand gestures show multivariate pattern representations in the human brain.
2017.

Rey Calvo, N., Reislev, N. L., Mortensen, E. L., Boraxbekk, C-J., Siebner, H. R. & Garde, E.
Analyses and characterisation of brain aging patterns - a cohort based multimodal MRI study.
2017.

Vestergaard, M., Krøis Holm, S., Uldall, P., Siebner, H. R., Paulson, O. B., Baaré, W. F. C. & Madsen, K. S.
Glucocorticoid treatment earlier in childhood and adolescence show dose-response associations with diurnal cortisol levels.
Developmental Psychobiology. 59, 8, p. 1010-1020, 2017.

Tomasevic, L., Takemi, M. & Siebner, H. R.
Synchronizing the transcranial magnetic pulse with electroencephalographic recordings effectively reduces inter-trial variability of the pulse artefact.
P L o S One. 12, 9 2017.

Thut, G., Bergmann, T. O., Fröhlich, F., Soekadar, S. R., Brittain, J-S., Valero-Cabré, A., Sack, A., Miniussi, C., Antal, A., Siebner, H. R., Ziemann, U. & Herrmann, C. S.
Guiding transcranial brain stimulation by EEG/MEG to interact with ongoing brain activity and associated functions: A position paper.
Clinical neurophysiology. 128, 5, p. 843-857, 2017.

Thomsen, B. L. C., Herz, D. M., Siebner, H. R. & Løkkegaard, A.
Dyskinesier ved Parkinsons sygdom: opdatering om nye billeddannende metoder og behandlingsmuligheder.
Ugeskrift for Laeger. 12, 2017, p. 2-6, 2017.

Szots, M., Blaabjerg, M., Orsi, G., Iversen, P., Kondziella, D., Madsen, C. G., Garde, E., Magnusson, P. O., Barsi, P., Nagy, F., Siebner, H. R. & Illes, Z.
Global brain atrophy and metabolic dysfunction in LGI1 encephalitis: A prospective multimodal MRI study.
Journal of the neurological sciences. 376, p. 159-165, 2017.

Suppa, A., Quartarone, A., Siebner, H., Chen, R., Di Lazzaro, V., Del Giudice, P., Paulus, W., Rothwell, J. C., Ziemann, U. & Classen, J.
The associative brain at work: Evidence from paired associative stimulation studies in humans.
Clinical neurophysiology. 128, 11, p. 2140-2164, 2017.

Stecker, M., Pasqualetti, P., Barry, R. J., Daskalakis, Z. J., Siebner, H. R. & Ziemann, U.
Statistical data analyses for clinical neurophysiology.
Clinical neurophysiology. 128, 10, p. 1837-1838, 2017.

Schreiber, K., Magyari, M., Sellebjerg, F., Iversen, P., Garde, E., Madsen, C. G., Börnsen, L., Romme Christensen, J., Ratzer, R., Siebner, H. R., Laursen, B. & Soelberg Sorensen, P.
High-dose erythropoietin in patients with progressive multiple sclerosis: A randomized, placebo-controlled, phase 2 trial.
Multiple sclerosis . 23, 5, p. 675-685, 2017.

Saturnino, G. B., Madsen, K. H., Siebner, H. R. & Thielscher, A.
How to target inter-regional phase synchronization with dual-site Transcranial Alternating Current Stimulation.
NeuroImage. 163, p. 68-80, 2017.

Ruiz, V. C., Andreasen , S. H., Petersen, T. H., Larsen, K. B., Madsen, K., Andersen, K. W., Akopian, I., Madsen, K. H., Hansen, C. P., Poulsen, I., Kammersgaard, L. P. & Siebner, H. R.
Alterations in the brain's connectome during recovery from severe traumatic brain injury: protocol for a longitudinal prospective study.
B M J Open. 7, 6, s. e016286 2017.

Reislev, N. H., Dyrby, T. B., Siebner, H. R., Lundell, H., Ptito, M. & Kupers, R.
Thalamocortical Connectivity and Microstructural Changes in Congenital and Late Blindness.
Neural Plasticity. 2017, p. 9807512, 2017.

Miskowiak, K. W., Svendsen, A-M. B., Harmer, C. J., Elliott, R., Macoveanu, J., Siebner, H. R., Kessing, L. V. & Vinberg, M.
Differences in neural and cognitive response to emotional faces in middle-aged dizygotic twins at familial risk of depression.
Psychological medicine. 47, 13, p. 2345-2357, 2017.

Miskowiak, K. W., Macoveanu, J., Jørgensen, M. B., Støttrup, M. M., Ott, C. V., Jensen, H. M., Jørgensen, A., Harmer, J., Paulson, O. B., Kessing, L. V. & Siebner, H. R.
Neural Response After a Single ECT Session During Retrieval of Emotional Self-Referent Words in Depression: A Randomized, Sham-Controlled fMRI Study.
International Journal of Neuropsychopharmacology. 21, 3, p. 226-235, 2017.

Miskowiak, K. W., Kjaerstad, H. L., Støttrup, M. M., Svendsen, A. M., Demant, K. M., Hoeffding, L. K., Werge, T. M., Burdick, K. E., Domschke, K., Carvalho, A. F., Vieta, E., Vinberg, M., Kessing, L. V., Siebner, H. R. & Macoveanu, J.
The catechol-O-methyltransferase (COMT) Val158Met genotype modulates working memory-related dorsolateral prefrontal response and performance in bipolar disorder.
Bipolar Disorders (English Edition, Print). 19, 3, p. 214-224, 2017.

Minjoli, S., Saturnino, G. B., Blicher, J. U., Stagg, C. J., Siebner, H. R., Antunes, A. & Thielscher, A.
The impact of large structural brain changes in chronic stroke patients on the electric field caused by transcranial brain stimulation.
NeuroImage. Clinical. 15, p. 106-117, 2017.

Michel Lange, V., Messerschmidt, M., Harder, P., Siebner, H. R. & Boye, K.
Planning and production of grammatical and lexical verbs in multi-word messages.
P L o S One. 12, 11 2017.

Madsen, K., Hesby, S., Poulsen, I., Fuglsang, S., Graff, J., Larsen, K. B., Kammersgaard, L. P., Law, I. & Siebner, H. R.
Comparison of Analytical Methods of Brain [(18)F]FDG-PET after Severe Traumatic Brain Injury.
Journal of Neuroscience Methods. 291, p. 176-181, 2017.

Lundell, H., Svolgaard, O., Dogonowski, A-M., Romme Christensen, J., Selleberg, F., Soelberg Sørensen, P., Blinkenberg, M., Siebner, H. R. & Garde, E.
Spinal cord atrophy in anterior-posterior direction reflects impairment in multiple sclerosis.
Acta Neurologica Scandinavica. 136, 4, p. 330-337, 2017.

Lehéricy, S., Vaillancourt, D. E., Seppi, K., Monchi, O., Rektorova, I., Antonini, A., McKeown, M. J., Masellis, M., Berg, D., Rowe, J. B., Lewis, S. J. G., Williams-Gray, C. H., Tessitore, A., Siebner, H. R. & International Parkinson and Movement Disorder Society -Neuroimaging Study Group.
The role of high-field magnetic resonance imaging in parkinsonian disorders: Pushing the boundaries forward.
Movement disorders. 32, 4, p. 510-525, 2017.

Karabanov, A. N., Ritterband-Rosenbaum, A., Christensen, M. S., Siebner, H. R. & Nielsen, J. B.
Modulation of fronto-parietal connections during the rubber hand illusion.
European Journal of Neuroscience. 45, 7, p. 964-974, 2017.

Friis-Olivarius, M., Hulme, O. J., Skov, M., Ramsøy, T. Z. & Siebner, H. R.
Imaging the Creative Unconscious: Reflexive Neural Responses to Objects in the Visual and Parahippocampal Region Predicts State and Trait Creativity.
Scientific Reports. 7, p. 1-8, 14420 2017.

Fisher, P. M., Larsen, C. B., Beliveau, V., Henningsson, S., Pinborg, A., Holst, K. K., Jensen, P. S., Svarer, C., Siebner, H. R., Knudsen, G. M. & Frokjaer, V. G.
Pharmacologically Induced Sex-Hormone Fluctuation Effects on Resting-State Functional Connectivity in a Risk Model for Depression: A Randomised Trial.
Neuropsychopharmacology. 42, 2, p. 446-453, 2017.

Dubbioso, R., Raffin, E., Karabanov, A., Thielscher, A. & Siebner, H. R.
Centre-surround organization of fast sensorimotor integration in human motor hand area.
NeuroImage. 158, p. 37-47, 2017.

Bianchi, F., Hjortkjær, J., Santurette, S., Zatorre, R. J., Siebner, H. R. & Dau, T.
Subcortical and cortical correlates of pitch discrimination: Evidence for two levels of neuroplasticity in musicians.
NeuroImage. 163, p. 398-412, 2017.

Antal, A., Alekseichuk, I., Bikson, M., Brockmöller, J., Brunoni, A. R., Chen, R., Cohen, L. G., Dowthwaite, G., Ellrich, J., Flöel, A., Fregni, F., George, M. S., Hamilton, R., Haueisen, J., Herrmann, C. S., Hummel, F. C., Lefaucheur, J-P., Liebetanz, D., Loo, C. K., McCaig, C. D., Miniussi, C., Miranda, P. C., Moliadze, V., Nitsche, M. A., Nowak, R., Padberg, F., Pascual-Leone, A., Poppendieck, W., Priori, A., Rossi, S., Rossini, P. M., Rothwell, J. C., Rueger, M. A., Ruffini, G., Schellhorn, K., Siebner, H. R., Ugawa, Y., Wexler, A., Ziemann, U., Hallett, M. & Paulus, W.
Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines.
Clinical neurophysiology. 128, 9, p. 1774-1809, 2017.

Ammitzbøll, C., Dyrby, T. B., Lyksborg, M., Schreiber, K., Ratzer, R., Romme Christensen, J., Iversen, P., Magyari, M., Garde, E., Sørensen, P. S., Siebner, H. R. & Sellebjerg, F.
Disability in progressive MS is associated with T2 lesion changes.
Multiple Sclerosis and Related Disorders. 20, p. 73-77, 2017.

Uhre, V. H. B., Baladi Nejad, A., Staugaard, C. F., Sørensen, K. H., Koch, S. V., Thomsen, P. H., Moltke, B. B., Vangkilde, S. A., Siebner, H. R. & Plessen , K. J.
Treatment Effects of Cognitive Therapy in Adolescents with OCD: Neural and Neurobiological Mediators of Effectiveness.
2016.

Svolgaard, O. M. R., Andersen, K. W., Bauer, C., Madsen, K. H., Iversen, P., Blinkenberg, M. B., Sellebjerg, F. T. & Siebner, H. R.
Motor fatigue scores correlate with task-related activity in cerebellum during a non-fatiguing precision grip task: a functional MRI study. .
2016.

Safeldt, M. G., Tomasevic, L., Karabanov, A., Siebner, H. R. & Madsen, K. H.
Towards Brain-State Dependent Transcranial Magnetic Stimulation: targeting the phase of oscillatory neocortical activity with singe-pulse TMS.
2 p., 2016.

McWalter, R. I., Hjortkjær, J., Siebner, H. R., Dau, T. & Madsen, K. H.
Sensitivity to sound texture statistics in auditory cortex.
1 p., 2016.

Macoveanu, J., Vinberg, M., Kessing, L. V., Siebner, H. R. & Baaré, W. F. C.
Unaffected twins discordant for affective disorders show changes in anterior callosal white matter microstructure.
2016.

MacWalter, R. I., Hjortkjær, J., Siebner, H. R., Dau, T. & Madsen, K. H.
Cortical sensitivity to auditory textures.
1 p., 2016.

Larsen, K. M., Pellegrino, G., Rosgaard Birknow, M., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, T. M., Siebner, H. R. & Mørup, M.
Genetic risk for schizophrenia is associated with an impaired auditory steady-state gamma response.
2016.

Lange, V. M., Siebner, H. R. & Boye, K.
Production of grammatical and lexical verbs in context: an ERP study.
2016.

Kesselheim, J., Takemi, M., Jønsson, M. G., Karabanov, A. & Siebner, H. R.
Exploiting I-Wave Rhythmicity To Optimizing The Stimulus-Response Relationship For TMS Of M1. 2016.

Karabanov, A., Irmen, F., Bisgaard, T. & Siebner, H. R.
Functional Plasticity During De Novo Acquisition of Laparoscopic Surgical Skills.
2016.

Hulme, O. J., Baladi Nejad, A., Haren, T., Henningsson, S., Madsen, K. H. & Siebner, H. R.
Psycho-Psychophysics: The Superior Temporal Sulcus and the Reflexive Decoding of Pain.
2016.

Dubbioso, R., Raffin, E. E., Karabanov, A., Haahr Nielsen, S., Thielscher, A. & Siebner, H. R.
SULCUS-BASED LINEAR MAPPING OF SENSORIMOTOR INTEGRATION IN THE HAND MOTOR AREA.
1 p., 2016.

Brunes, P. T., Tomasevic, L., Siebner, H. R., Schmidt, M. N. & Madsen, K. H.
Continuous Phase Tracking of Cortical Oscillatory Activity with Scalp EEG.
2016.

Bicalho Saturnino, G., Siebner, H. R., Madsen, K. H. & Thielscher, A.
Feasibility of focused multichannel optimization of transcranial current stimulation.
1 p., 2016.

Bianchi, F., Hjortkjær, J., Santurette, S., Siebner, H. R. & Dau, T.
Complex-tones cortical pitch representations in musicians vs. non-musicians.
1 p., 2016.

Bauer, C., Andersen, K. W., Svolgaard, O. M. R., Sellebjerg, F. T., Madsen, K. S., Madsen, K. H., Dyrby, T. B. & Siebner, H. R.
Microstructural white matter correlates of motor fatigue in multiple sclerosis: a diffusion weighted imaging study. .
2016.

Bauer, C., Andersen, K. W., Svolgaard, O. M. R., Madsen, K. H., Dyrby, T. B., Sellebjerg, F. T. & Siebner, H. R.
Is there a regional structural correlate of motor fatigue in multiple sclerosis?: a Magnetic Resonance Imaging study.
2016.

Baruël Johansen, L., Madsen, K. S., Andersen, K. W., Madsen, K. H., Siebner, H. R. & Baaré, W. F. C.
Reduced global efficiency and orbitofrontal centrality of the functional brain network characterizes high neuroticism in adolescence.
2016.

Andersen, K. W., Madsen, K. H., Dyrby, T. B. & Siebner, H. R.
Multi Voxel Pattern Analysis (MVPA) classification reveals distributed neural presentations of specific finger movement sequences in the human striatum: a task-based functional MRI study.
2016.

Andersen, K. W., Madsen, K. H., Dyrby, T. B. & Siebner, H. R.
Shift of finger sequence representations in the human basal ganglia during motor learning.
2016.

Dogonowski, A-M., Blinkenberg, M., Paulson, O. B., Sellebjerg, F., Sørensen, P. S., Siebner, H. R. & Madsen, K. H.
Recovery from an acute relapse is associated with changes in motor resting-state connectivity in multiple sclerosis.
Journal of neurology, neurosurgery, and psychiatry. 87, p. 912-914 (2016).

Karabanov, A., Lohse, A. & Siebner, H. R.
Hjernestimulation og Den forudsigende hjerne.
Den forudsigende hjerne. Hjerneforum, p. 46-52 (2016).

Vangkilde, A., Jepsen, J. R. M., Schmock, H., Olesen, C., Arnarsdóttir, S., Baaré, W. F. C., Plessen, K. J., Didriksen, M., Siebner, H. R., Werge, T. & Olsen, L.
Associations between social cognition, skills, and function and subclinical negative and positive symptoms in 22q11.2 deletion syndrome.
Journal of Neurodevelopmental Disorders. 8, 1, 13 p., 42 (2016).

Reislev, N. L., Kupers, R., Siebner, H. R., Ptito, M. & Dyrby, T. B.
Blindness alters the microstructure of the ventral but not the dorsal visual stream.
Brain structure & function. 221, 6, s. pp 2891-2903 13 p. (2016).

Reislev, N. L., Dyrby, T. B., Siebner, H. R., Kupers, R. & Ptito, M.
Simultaneous assessment of white matter changes in microstructure and connectedness in the blind brain.
Neural Plasticity. 2016, p. 1-12, Article ID 6029241 (2016).

Ratzer, R., Iversen, P., Börnsen, L., Dyrby, T. B., Romme Christensen, J., Ammitzbøll, C., Madsen, C. G., Garde, E., Lyksborg, M., Andersen, B., Hyldstrup, L., Sørensen, P. S., Siebner, H. R. & Sellebjerg, F.
Monthly oral methylprednisolone pulse treatment in progressive multiple sclerosis.
Multiple sclerosis . 22, 7, p. 926-934 (2016).

Ponseti, J., Granert, O., Van Eimeren, T., Jansen, O., Wolff, S., Beier, K., Deuschl, G., Huchzermeier, C., Stirn, A., Bosinski, H. & Siebner, H. R.
Assessing paedophilia based on the haemodynamic brain response to face images.
The world journal of biological psychiatry. 17, 1, p. 39-46 (2016).

Miskowiak, K. W., Vinberg, M., Glerup, L., Paulson, O. B., Knudsen, G. M., Ehrenreich, H., Harmer, C. J., Kessing, L. V., Siebner, H. R. & Macoveanu, J.
Neural correlates of improved executive function following erythropoietin treatment in mood disorders.
Psychological medicine. 46, 8, p. 1679-91 (2016).

Miskowiak, K. W., Macoveanu, J., Vinberg, M., Assentoft, E., Randers, L., Harmer, C. J., Ehrenreich, H., Paulson, O. B., Knudsen, G. M., Siebner, H. R. & Kessing, L. V.
Effects of erythropoietin on memory-relevant neurocircuitry activity and recall in mood disorders.
Acta Psychiatrica Scandinavica. 134, 3, p. 249-59 (2016).

Meder D, Haagensen BN, Hulme H, Morville T, Gelskov S, Herz DM, Diomsina B, Christensen MS, Madsen KH, Siebner HR (2016) Tuning the brake while raising the stake: Network dynamics during sequential decision-making. J Neurosci 36:5417-5426.

Meder D, Madsen KH, Hulme O, Siebner HR (2016) Chasing probabilities - Signaling negative and positive prediction errors across domains. Neuroimage 134:180-191.

Madsen, M. K., Mc Mahon, B., Andersen, S. B., Siebner, H. R., Knudsen, G. M. & Fisher, P. M.
Threat-related amygdala functional connectivity is associated with 5-HTTLPR genotype and neuroticism.
Social Cognitive and Affective Neuroscience. 11, 1, p. 140-149 (2016).

Macoveanu, J., Vinberg, M., Madsen, K., Kessing, L. V., Siebner, H. R. & Baaré, W.
Unaffected twins discordant for affective disorders show changes in anterior callosal white matter microstructure.
Acta Psychiatrica Scandinavica. 134, 5, p. 441-451 (2016).

Macoveanu, J., Henningsson, S., Pinborg, A., Jensen, P., Knudsen, G. M., Frokjaer, V. G. & Siebner, H. R.
Sex-Steroid Hormone Manipulation Reduces Brain Response to Reward.
Neuropsychopharmacology. 41, p. 1057-1065 (2016).

Macoveanu J, Fisher PM, Madsen MK, Mc Mahon B, Knudsen GM, Siebner HR (2016) Bright-light intervention induces a dose-dependent increase in striatal response to risk in healthy volunteers. NeuroImage 139:37-43.

Løkkegaard A, Herz DM, Haagensen BN, Lorentzen AK, Eickhoff SB, Siebner HR (2016) Altered sensorimotor activation patterns in idiopathic dystonia - an activation likelihood estimation meta-analysis of functional brain imaging studies. Hum Brain Mapp 37:547-557. 

Laursen, H. R., Henningsson, S., Macoveanu, J., Jernigan, T. L., Siebner, H. R., Holst, K. K., Skimminge, A., Knudsen, G. M., Ramsoy, T. Z. & Erritzoe, D.
Serotonergic neurotransmission in emotional processing: New evidence from long-term recreational poly-drug ecstasy use.
Journal of psychopharmacology. 30, 12, p. 1296-1304 (2016).

Knudsen, G. M., Jensen, P. S., Erritzoe, D., Baaré, W. F. C., Ettrup, A., Fisher, P. M., Gillings, N., Hansen, H. D., Hansen, L. K., Hasselbalch, S. G., Henningsson, S., Herth, M. M., Holst, K. K., Iversen, P., Kessing, L. V., Macoveanu, J., Madsen, K. S., Mortensen, E. L., Nielsen, F. Å., Paulson, O. B., Siebner, H. R., Stenbæk, D. S., Svarer, C., Jernigan, T. L., Strother, S. C. & Frokjaer, V. G.
The Center for Integrated Molecular Brain Imaging (Cimbi) database.
NeuroImage. 124, p. 1213-1219 (2016).

Karabanov A, Thielscher A, Siebner HR (2016) Transcranial brain stimulation: closing the loop between brain and stimulation. Curr Opin Neurol 29:397-404.

Jung, N. H., Gleich, B., Gattinger, N., Hoess, C., Haug, C., Siebner, H. R. & Mall, V.
Quadri-Pulse Theta Burst Stimulation using Ultra-High Frequency Bursts - A New Protocol to Induce Changes in Cortico-Spinal Excitability in Human Motor Cortex.
P L o S One. 11, 12, s. e0168410 15 p. (2016).

Herz, D. M., Haagensen, B. N., Haahr Nielsen, S., Madsen, K. H., Løkkegaard, A. & Siebner, H. R.
Resting-state connectivity predicts levodopa-induced dyskinesias in Parkinson's disease.
Movement disorders. 31, 4, p. 521-529 (2016).

Hartwigsen, G., Weigel, A., Schuschan, P., Siebner, H. R., Weise, D., Classen, J. & Saur, D.
Dissociating Parieto-Frontal Networks for Phonological and Semantic Word Decisions: A Condition-and-Perturb TMS Study.
Cerebral Cortex. 26, 6, p. 2590-2601 (2016).

Gelskov SV, Madsen KH, Ramsøy TZ *, Siebner HR * (* equal contribution) 2016 Aberrant neural signatures of decision-making: pathological gamblers display cortico-striatal hypersensitivity to extreme gambles. NeuroImage 128:342-352. 

Gaist D*, Grade E*, Blaabjerg M, Nielsen H, Krøigård T, Østergaard K, Settergren H,  von Bornemann Hjelmborg J, Madsen CG, Iversen P, Kyvik KO, Siebner HR, Ashina M (2016) MD, PhD, DMScMigraine with aura and risk of silent brain infarcts and white matter hyperintensities: A population-based MRI study of female Danish twins. Brain 139:2015-2023.

Eriksen, C. S., Garde, E., Reislev, N. L., Wimmelmann, C. L., Bieler, T., Ziegler, A. K., Gylling, A. T., Dideriksen, K. J., Siebner, H. R., Mortensen, E. L. & Kjaer, M.
Physical activity as intervention for age-related loss of muscle mass and function: protocol for a randomised controlled trial (the LISA study).
B M J Open. 6, 12, e012951 (2016).

Bergmann TO, Karabanov A, Hartwigsen G, Thielscher A, Siebner HR (2016) Combining non-invasive transcranial brain stimulation with neuroimaging and electrophysiology: current approaches and future perspectives. NeuroImage 140:4-19.

Angstmann S, Madsen KS, Skimminge A, Jernigan TL, Baaré WFC, Siebner HR (2016) Microstructural asymmetry of the corticospinal tracts predicts right-left differences in circle drawing skill in right-handed adolescents. Brain Struct Funct 221:4475-4489.

Raffin E*, Pellegrino G*, Di Lazzaro V, Thielscher A, Siebner HR (2015) Bringing transcranial mapping into shape: Sulcus-aligned mapping captures motor somatotopy in human primary motor hand area. NeuroImage 120:164–175. * Shared first authors.

Miskowiak KW, Vinberg M, Macoveanu J, Ehrenreich H, Køster N, Inkster B, Paulson OB, Kessing LV, Skimminge A, Siebner HR (2015) Effects of erythropoietin on hippocampal volume and memory in mood disorder: a randomized, placebo-controlled study. Biol Psychiat 8:270-277. 

Herz DM, Haagensen BN, Christensen MS, Madsen KH, Rowe JB, Løkkegaard A, Siebner HR (2015) Abnormal dopaminergic modulation of striato-cortical networks underlies levodopa-induced dyskinesias in humans. Brain 138:1658-1666.

Herz DM, Haagensen BN,Christensen MS, Madsen KH, Rowe J, Løkkegaard A, Siebner HR (2014) The acute brain response to levodopa heralds dyskinesias in Parkinson’s disease. Ann Neurol 75:829-36. 

Herz DM, Christensen MS, Bruggemann N, Hulme OJ, Ridderinkhof KR, Madsen KH, Siebner HR (2014) Motivational tuning of fronto-subthalamic connectivity facilitates control of action impulses. J Neurosci 34:3210-7.

van der Vegt JPM, Hulme OJ, Zittel S, Madsen KH, Weiss MM, Buhmann C, Bloem BR, Münchau A, Siebner HR (2013) Attenuated neural response to gamble outcomes in drug-naive patients with Parkinson’s disease. Brain 136:1192-1203. 

Macoveanu J, Rowe JB, Hornboll B, Elliott R, Paulson OB, Knudsen GM, Siebner HR (2013) Serotonin 2A receptors contribute to the regulation of risk-averse decisions. NeuroImage 83:35-44.

Kassuba T, Menz MM, Röder B, Siebner HR (2013) Multisensory interactions between auditory and haptic object recognition. Cereb Cortex 23:1097-1107. 

Hartwigsen G, Saur D, Price CJ, Baumgaertner A, Ulmer S, Siebner HR (2013) Perturbation of left posterior inferior frontal gyrus triggers adaptive plasticity in the right homologue during speech production. Proc Natl Acad Sci USA 110:16402-7. 

van Nuenen BFL, Kuhtz-Buschbeck J, Schulz C, Bloem BR, Siebner HR (2012) Weight-specific anticipatory coding of grip force in human dorsal premotor cortex. J Neurosci 32:5272-83. 

Hartwigsen G, Bestmann S, Ward NS, Woerbel S, Mastroeni C, Granert O, Siebner HR (2012) Left dorsal premotor cortex and supramarginal gyrus complement each other during rapid action reprogramming. J Neurosci 32:16162-71. 

Groppa S, Werner-Petroll N, Münchau A, Deuschl G, Ruschworth MF, Siebner HR (2012) Novel dual-site transcranial magnetic stimulation paradigm to prob fast facilitatory inputs from ipsilateral dorsal premotor cortex to primary motor cortex Neuroimage 62 500-9. 

Bergmann TO, Mölle M, Schmidt M, Lindner C, Marshall L, Born J, Siebner HR (2012). EEGguided TMS reveals rapid shifts in motor cortical excitability during the human sleep slow oscillation. J Neurosci. 32:243-53.