News

Here you will find all the latest news about DRCMR and the researchers and students working at the centre.

April 20th 2010,  "Basse" delivered two new scanners for the DRCMR at Hvidovre Hospital.
Mette Hauge Lauritzen received a poster award at the ISMRM.At the Joint Annual Meeting of the ISMRM and ESMRMB in Stockholm last week Mette Lauritzen received a poster award for her poster entitled "Visualizing Regional Changes in Metabolism in a Rat Model of Acute Myocardial Infarction Using Hyperpolarized 13C MR". The work was presented as an e-poster and got a third prize in the category "Spec, Hype and the Like: The 1000 Club".
Does a conflict between inborn preferences and educational standards during childhood impact the structure of the adult brain? In a new study published in Journal of Neuroscience, Hartwig R. Siebner from the DRCMR , and co-workers demonstrated that left-handed people being forced to use their right hand acquire structural brain changes. The results are in accordance with a more general recent finding: The brain changes shape depending on its use. Full reference:J Neurosci. 2010 Mar 3;30(9):3271-5.Nurture versus nature: Long-term impact of forced right-handedness on structure of pericentral cortex and basal ganglia. Klöppel S, Mangin JF, Vongerichten A, Frackowiak RS, Siebner HR. 
An international multi-center study with DRCMR involvement was just published in the renowned journal PNAS. Anne-Marie Dogonowski and Kristoffer H. Madsen are co-authors of this resting state fMRI study on functional connectivity together with other experts in the field of brain connectivity measurements.Full reference:Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4734-9.Toward discovery science of human brain function.Biswal BB, Mennes M, Zuo XN, Gohel S, Kelly C, Smith SM, Beckmann CF, Adelstein JS, Buckner RL, Colcombe S, Dogonowski AM, Ernst M, Fair D, Hampson M, Hoptman MJ, Hyde JS, Kiviniemi VJ, Kötter R, Li SJ, Lin CP, Lowe MJ, Mackay C, Madden DJ, Madsen KH, Margulies DS, Mayberg HS, McMahon K, Monk CS, Mostofsky SH, Nagel BJ, Pekar JJ, Peltier SJ, Petersen SE, Riedl V, Rombouts SA, Rypma B, Schlaggar BL, Schmidt S, Seidler RD, Siegle GJ, Sorg C, Teng GJ, Veijola J, Villringer A, Walter M, Wang L,…
 A number of PhD-stipends are announced for enrollment at the Copenhagen Graduate School of Health Sciences at The Faculty of Health Sciences, University of Copenhagen. Several of the projects have DRCMR involvement. 
Kristoffer Hougaard Madsen from the DRCMR recently received "Direktør Gorm-Petersens Mindelegat" given in recognition of his PhD thesis entitled "Modelling Strategies for Functional Magnetic Resonance Imaging" . Further details are given in Danish on the DTU homepage .
The special Neuroscience issue on imaging genetics A special issue on imaging genetics is published in the journal Neuroscience. Professor Hartwig R. Siebner from the DRCMR is primary author of the editorial , is co-authoring two articles, and is guest-editing this issue that will be featured in the Elsevier booth at the Society for Neuroscience annual meeting. Special Issue:Linking Genes to Brain Function in Health and DiseaseGuest EditorsJoseph Callicott, MDVenkata Mattay, MDHartwig R. Siebner, MDTobias Sommer, MD
Free educational MR software developed at the DRCMR got the  ESMRMB software award at the society meeting  in Turkey, October 2009. The software includes the Bloch Simulator and a new instructive java applet allowing students to explore the simplest Magnetic Resonance setup possible. Both are available via http://www.drcmr.dk/MR together with explanatory texts, animations and links to extensive MRI course notes in English.
Fremover vil Thomas Z. Ramsøy fra DRCMR og CBS blogge om hjerneforskning på Videnskab.dk. Han lægger ud med en advarsel om hjerneforskning , og en artikel om hvordan fosterets hjerneceller kan finde vej til moderens hjerne. Læse mere i  Hjernebloggen.
 Download course program  Overview: This advanced PhD course will provide an up-to-date overview of the currentlyavailable magnetic resonance imaging (MRI) techniques to study the human brain.Emphasis will be placed on new methodological advances in structural and functional MRI.Aims: to acquire an in-depth understanding of the various neuroscientific MRI tools; to beable to efficiently plan and conduct neuroscientific MRI studies; to select the optimal MRIprotocol and data analysis method for individual research projects; and to be able to criticallyinterpret published MRI studies.Content: Morphometric analyses of high-resolution structural MRI images of the brain (voxeland tensor based morphometry, cortical thickness mapping, shape analysis, classification).Diffusion weighted MRI - assessing anatomical connectivity in vivo (micro- and macrostructural neuroanatomy, diffusion tensor imaging, TBSS, tractrography and connectivity, clinicalapplications). Functional MRI - mapping the brain at rest and at work with a focus on dataprocessing (perfusion MRI and BOLD, paradigm design, meta-analysis, second level analysis,causality and connectivity analysis,…
A number of student projects (BSc/MSc) are available in the field of Magnetic Resonance Imaging. Some of those are described in a flyer prepared for students at the DTU Medicine&Technology education. Let us know, if you are interested in these projects, or similar.
MRI lecture notes written by Lars G. Hanson were only available in Danish until now. They have now been translated into English by Theis Groth. The notes offer a thorough introduction to basic MRI concepts and imaging techniques. They are meant to supplement lectures aimed at new students of MRI, whether these are trained in physics or not. Important concepts are explained rigorously without the use of math. Supplementary sofware and animations are available at http://www.drcmr.dk/MR The notes are avaiable in two PDF versions for printing on the paper formats A4 or Letter: Introduction to Magnetic Resonance Imaging Techniques. 
  The DRCMR annual report 2008 is now available in PDF files optimised for screen an printing. The report provides an overview of the research and clinical activities. 
Professor Hartwig R. Siebner from the DRCMR has together with researcher from Christian-Albrechts-Universität in Kiel, Germany, explored how sexual preference is revealed in functional MRI using erotic visual stimuli. The group found fMRI to be at least as sensitive as phallometry, which is used as evidence in trials, but which is criticized. Also, the brain response of homosexuals was found to be similar to that of heterosexuals, confirming that the brains of homosexuals are normal, only tuned to different stimuli. The paper was published in Journal of Sexual Medicine: Assessment of sexual orientation using the hemodynamic brain response to visual sexual stimuli'; doi: 10.1111/j.1743-6109.2009.01233.x An article in Danish summarizing the study was published by Thomas Hoffmann at Videnskab.dk: Hjerneskanninger afslører din sex-fantasi  
A concensus paper written by 31 recognized international experts has just been published with Professor Hartwig R. Siebner from the DRCMR as first author. The paper serves as an important reference for future work in this rapidly evolving research field.  The paper is available at the Brain Stimulation website, and it is entitled Concensus paper: Combining transcranial stimulation with neuroimaging. Authors:  Hartwig R. Siebner, MD, Til O. Bergmann, MD, Sven Bestmann, MD, Marcello Massimini, MD, Heidi Johansen-Berg, MD, Hitoshi Mochizuki, MD, Daryl E. Bohning, MD, Erie D. Boorman, MD, Sergiu Groppa, MD, Carlo Miniussi, MD, Alvaro Pascual-Leone, MD, Reto Huber, MD, Paul C.J. Taylor, MD, Risto J. Ilmoniemi, MD, Luigi De Gennaro, MD, Antonio P. Strafella, MD, Seppo Kähkönen, MD, Stefan Klöppel, MD, Giovanni B. Frisoni, MD, Mark S. George, MD, Mark Hallett, MD, Stephan A. Brandt, MD, Matthew F. Rushworth, MD, Ulf Ziemann, MD, John C. Rothwell, MD, Nick Ward, MD, Leonardo G. Cohen, MD, Jürgen Baudewig, MD, Tomáš Paus, MD, Yoshikazu Ugawa, MD, Paolo M. Rossini, MD
The annual report of the Center for Integrated Molecular Imaging, Cimbi, is available for download at the Cimbi homepage. The focus of Cimbi is nothing less than the neural basis of personality,  and the report contains enlightning articles on this subject of research. Magnetic Resonance Imaging is an important tool in this context and important contributions from DRCMR researchers are consequently found in most Cimbi subprojecs.
An article involving significant contributions from the DRCMR has just appeared in the prestigious journal The Lancet Neurology.The article evaluates the efficacy of a new combination treatment for Multiple Sclerosis. The described international multi-center study was partially based on MR images aquired at the DRCMR at Hvidovre Hospital. The data analysis was developed and conducted in the DRCMR Reader Centre, which is an evaluation center for international drug trials involving MRI. Co-author Lise Vejby Søgaard represents the Reader Centre. The paper can be found on the The Lancet's homepage and it is entitled NORdic trial of oral Methylprednisolone as add-on therapy to Interferon beta-1a for treatment of relapsing-remitting Multiple Sclerosis (NORMIMS study): a randomised, placebo-controlled trial. 
Hartwig R. Siebner has been appointed professor at the DRCMR, Copenhagen University Hospital Hvidovre. Congratulations!Inauguration speech"Watching the brain at work: insights into human brain function with magnetic resonance imaging"Monday 15th of June 2009 13.00-14.00Auditorium 3+4, section 154Hvidovre HospitalAfter the talk, the board of the hospital hosts a reception in "Det Grønne Rum", Vandrehallen 1st floor (14.00-16.00)
On March 31st 2009, MD Annette Sidaros succesfully defended  her Ph.D. thesis entitledMRI in severe traumatic brain injury: Micro- and macrostructural changes The work was performed at the Danish Research Centre for Magnetic Resonance and at the Department of Neurohabilitation, both at Copenhagen University Hospital Hvidovre. Follow the link above to download thesis. The comitee:Professor John Whyte, Philadelphia, USAProfessor Jens Christian H. Sørensen, ÅrhusProfessor Carsten Thomsen, København.Supervisors: DMSc Olaf B. Paulson, DMSc Aase W. Engberg, DMSc Egill Rostrup. PhD Terry L. Jernigan, DMSc Palle Petersen.Abstract in English:  The principal aim of the present PhD project was to study quantitatively the long-term microand macrostructural brain changes in survivors from severe traumatic brain injury (TBI). A total of 31 patients admitted for early rehabilitation following severe TBI were included and underwent magnetic resonance imaging (MRI), including Diffusion Tensor Imaging (DTI), at mean 8 weeks post-injury. Follow-up MRI at mean 12 months post-injury…
Workshop on Diffusion weighted MRI Time: Monday March 16, 14:30 – 17:00Location: Auditorium 3+4 placed at the ground floor near the main entrance at Hvidovre HospitalHomepage: www.drcmr.dkAttendance is free of chargeRegistration, please send a mail with name to timd (at) drcmr.dkWe hereby invite everybody who has an interest - or is just curious - to join this workshop at the Danish Research Centre for Magnetic Resonance (DRCMR). The workshop will cover cutting-edge methods within the field of diffusion weighted MRI.Diffusion weighted imaging (DWI) is a technique that measures the restricted diffusion of water molecules within brain tissue. Although measurements are obtained at the macroscopic level (cubic millimetre range), DWI provides information about the microstructure of the tissue and enables the visualization of fibre tracts. The program covers a wide range of topics. Martin Vestergaard Hansen (DRCMR) will demonstrate how diffusion MRI can be used to study brain maturation in children.…
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